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Biological effects: Aflatoxins are acute hepatotoxins and are known to be carcinogenic in some animal species as rat. Aflatoxin B1 is acutely toxic and is responsible for liver necrosis. The toxicological effects of the aflatoxins are influenced by their metabolism after intake into their body.
Figure: Representation of the metabolism of aflatoxin and its biological effects
When cows eat feed containing aflatoxin, aflatoxin M1 and M2 is excreted in the milk. Although M1 and M2 are less toxic than the parent compound B1, M1 retains its toxic and carcinogenic ability in many animals. The LD50 of AFB1 for rats by the oral route is 1.2mg/kg and 1.5 to 2.0 mg/kg for AFG1.
Pasteurellosis Haemorrhagic septicaemia (HS) Synonym : Gal Ghotu Causative organism B:2 : Pasteurella multocida Serotype Haemorrhage sept
Self Help Group: The first and perhaps the most influential of substance abuse rehabilitation is Self Help Group. The self help programme was founded in 1935 by two men, Dr. B
Define etiological risk factors in cancer - Genetic Factors? Some cancers are programmed by genes to develop. Gene mutations result from one or more regulatory genes in the cel
LIPOIDA L MODELS According to Overton (1902) plasma membrane consists of single layer of lipid, because cell permeability is related to lipids. According to Gorter and
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Explain Monascus species Most of the reports of food colourants from microbial sources involve Monascus species, particularly Monascus purpureus, followed by Rhodotorula speci
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Define isolated soybean proteins in Cereal products? ISP is sometimes used instead of, or in combination with isolates and soy flour, in the formulation of milk replacer mixtur
difference between RBC and WBC for homework
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