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Biological effects: Aflatoxins are acute hepatotoxins and are known to be carcinogenic in some animal species as rat. Aflatoxin B1 is acutely toxic and is responsible for liver necrosis. The toxicological effects of the aflatoxins are influenced by their metabolism after intake into their body.
Figure: Representation of the metabolism of aflatoxin and its biological effects
When cows eat feed containing aflatoxin, aflatoxin M1 and M2 is excreted in the milk. Although M1 and M2 are less toxic than the parent compound B1, M1 retains its toxic and carcinogenic ability in many animals. The LD50 of AFB1 for rats by the oral route is 1.2mg/kg and 1.5 to 2.0 mg/kg for AFG1.
Internal Factor - Factors Controlling Metamorphosis in Insects Likewise to the amphibian metamorphosis, moulting and metamorphosis in insects has been found to be initiated in
The American Heart Association (AHA) has recommended the revised Jones Criteria as a guide for ARF diagnosis. The same have been approved by WHO study group for the diagnosis of in
Pituitary The pituitary is also known as hypophysis. It is composed of two embryologically distinct tissue. The anterior pituitary or adenohypophysis is derived from the roof
Q. How Genes can be exchanged between chromatids? When two homologous chromosomes physically exchangecorresponding segments during prophase I of meiosis, geneticists call it cr
Define the major source of vitamin A? The major source of vitamin A, as you may be aware, is the carotenoid pigments which are synthesized by plants. Several carotenoid possess
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Summer Stratification - Thermal stratification Thermal stratification is fairly pronounced during the summer seasons in most lakes of the temperate (cold) regions but is rare
Q. Besides being fundamental for the activation of the main gastric digestive enzyme how does HCl also directly participate in digestion? With its corrosive effect HCl also hel
Why is the dietary obtainment of iodine so important for thyroid functioning? The obtainment of iodine from the diet is significant for the thyroid because this chemical elemen
CONJUG A TE D PROTEINS Besides being made of polypeptides, the conjugated proteins posses additional groups, metals or ions. Consists of protein and non-protein parts.
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