Define genetic susceptibility factors for obesity, Biology

Assignment Help:

Define Genetic Susceptibility Factors for Obesity?

Some people inherit a tendency to become fat. Earlier, it was thought that genetic inheritance ranged from 66% to 80% but now it is believed that our chances of inheriting our parent's BMI is about 33%. Obesity or thinness of an individual is inherited, basically from the biological mother. If our biological mother has been overweight as an adult, the likelihood of our being heavy is about 75%. A number of genes are implicated in pathogenesis of obesity: The two genes which recently have received much attention are the ob gene and the β3 - adrenoreceptor gene. The ob gene produces leptin (a hormone) which is normally secreted from fat cells. Mutations in the ob gene cause obesity. Treatment of obese mice with leptin has shown to reduce food intake and body fat. Some scientists are of the opinion that the ob gene may not have a major role to play in human obesity. The β3 - adrenoreceptor gene is basically located in adipose tissue. It regulates Resting Metabolic Rate and oxidation of fat in human beings. A mutation in this gene may lead to weight gain. In some individuals, it may increase the body's ability to store fat when food is limited and cause an increased risk of obesity when plenty of food is available and energy expenditure is reduced. However, this does not mean that it is inevitable for a person to be obese because of genetic mutations. Expression of the genetic tendency may be controlled by appropriate life style modifications also.


Related Discussions:- Define genetic susceptibility factors for obesity

Concept of digestion in the stomach, Digestion in the Stomach To unders...

Digestion in the Stomach To understand  the digestion mechanism  in the stomach, it is important to know about the anatomy of the stomach. Look up Unit 6, in the Applied Physio

Explain the changes in cell wall and intercellular structure, Explain the c...

Explain the changes in cell wall and intercellular structure As a result of changes in the cell wall and intercellular structure, all fruits and vegetables undergo softening wh

Enzyme - linked immunosorbent assay (elisa), E n z y m e - l...

E n z y m e - linked immunosorbent assay (ELISA):   ELISA in its var io us modifications e.g. plate ELISA, sandwich ELISA, competitive ELISA, ELISA strip or

How does the contraceptive diaphragm work, How does the contraceptive diaph...

How does the contraceptive diaphragm work? What are the limitations of this contraceptive method? The contraceptive diaphragm is an artifact made of latex or plastic that when

Agro industrial-chelating agents, Chelating agents Oxalates: Only a ...

Chelating agents Oxalates: Only a few plants contain sufficient amounts of sodium and potassium oxalate to be considered toxic. Moreover, ruminants that consume these plants

Method of purchasing a service, Normal 0 false false false ...

Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Define the role of fluorine in human body, Define the role of Fluorine in H...

Define the role of Fluorine in Human Body? Fluorine is potentially a toxic element. Its essentiality for humans is not established although the role of fluoride in providing pr

State the purpose of a neuropsychological screening, State the purpose of a...

State the purpose of a neuropsychological screening The purpose of a neuropsychological screening examination is to determine if there is reasonable evidence, beyond initial cl

Define the prevention of iron deficiency anaemia, Define the Prevention of ...

Define the Prevention of iron deficiency anaemia? As in the case of vitamin A deficiency, correction and prevention of dietary inadequacy of iron are important sustainable meth

Phylum protozoa, PHYLUM  PROTOZOA Definition  and  Introduction  ...

PHYLUM  PROTOZOA Definition  and  Introduction  All  unicellular ( or  acellular )  eukaryotic  animals. Most  primitive (Gr. Protos = first=zoon= animals ) organisms

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd