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Define Effect of feeding method on drug availability?
The form in which a drug is administered or enters the body can influence its absorption, metabolism or excretion. This becomes more pronounced among critically ill patients who cannot consume drugs orally and are on enteral food support. If the drug has to be administered though the enteral feeding tube it needs to be either crushed or dissolved in a solvent. Crushing oral preparations to pass down the tube may alter their absorption time/activity.
Some of the drugs cannot be added to the food infusion as it may alter their stability. Several drugs are available only in the form of tablets or capsules, dissolving these in feed, water, alcohol or sorbitol may not always be feasible. Drug such as cimetidine, aluminium hydroxide, metaclorpromide are physically incompatible with enteral foods. Certain drugs like phenytoin form complexes with calcium and protein thereby resulting in markedly reduced absorption of this medication. Such drugs need to given only by stopping enteral feed infusions for 1-2 hours. Patients on total parenteral nutrition generally have a separate tube (catheter) for infusion of drugs. Toxicity/over dosage of drugs is frequently observed in case of certain drugs administered directly into the blood.
Sporozoans – Protozoan Sporozoans of the genus Plasmodium are responsible for causing a serious human disease, malaria. They are among, the best known parasites which live in
difference between axon and cyton
High Energy Compounds Primary need of the animal body from the nutrients is energy. Free energy is the term used to denote the energy available to do useful work. Anabolic or synth
How many asymmetric carbons does the amino acid serine have? Please explain with a strucutral diagram if possible.
What ions must a plant obtain from the soil in order to make (a) ATP, (b) chlorophyll? (a) To create ATP (adenosine triphosphate) a plant requires a supply of phosphate io
1. You have two bags of polymer. Bag A has 10 kgs of polymer with weight average molecular weight of 336.6 kg and Bag B has 20kg of polymer with weight average molecular weight 39
what are the two benefits of fever with explaination??
Prevention You as nurse needs to ensure that iron supplementation is given to children who are at risk for iron deficiency. Iron supplementation should start between 4 and
what is taxonomy
Candida albicans, and Aspergillus species are the most common of the many fungal organisms identified as causing IE. Fungal endocarditis arises in specific settings. Valve replace
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