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Define Effect of feeding method on drug availability?
The form in which a drug is administered or enters the body can influence its absorption, metabolism or excretion. This becomes more pronounced among critically ill patients who cannot consume drugs orally and are on enteral food support. If the drug has to be administered though the enteral feeding tube it needs to be either crushed or dissolved in a solvent. Crushing oral preparations to pass down the tube may alter their absorption time/activity.
Some of the drugs cannot be added to the food infusion as it may alter their stability. Several drugs are available only in the form of tablets or capsules, dissolving these in feed, water, alcohol or sorbitol may not always be feasible. Drug such as cimetidine, aluminium hydroxide, metaclorpromide are physically incompatible with enteral foods. Certain drugs like phenytoin form complexes with calcium and protein thereby resulting in markedly reduced absorption of this medication. Such drugs need to given only by stopping enteral feed infusions for 1-2 hours. Patients on total parenteral nutrition generally have a separate tube (catheter) for infusion of drugs. Toxicity/over dosage of drugs is frequently observed in case of certain drugs administered directly into the blood.
DISORDE R RELATED TO NUTRITION AND DIGESTIVE SYSTEM Malnutrition Malnutrition is improper intake of food. Malnutrion covers both undernutrition and overnutrition. Und
What happens to a cell when placed in a salt solution and then into distilled water?
A) Maintain structural integrity of the cell B) Regulate the movement of substances into and out of the cell C) Provide communication between the cells D) ALl of the above
How to Calculate the Requirements for the Calcium in Body? Requirements for calcium depend upon the rate at which calcium is incorporated into bone; they are therefore highest
Q. Signs and Symptoms diabetic ketoacidosis? The following are the signs and symptoms of DKA: 1) Increased heart rate (tachycardia) 2) Low blood pressure 3) Dehydratio
THE PHYSIOLOGY OF LACTATION
Medical Records This includes: health history of patient/client a report of the findings on examination signs and symptoms observation records progress
Issues to be addressed by counsellor while counselling a diabetic patient The following issues should also be addressed while counselling a diabetic patient and their family me
Give an example of how the public perception of science has been distorted or manipulated to serve an alternative purpose.
Blastomycosis Blastomyces dermatidis is a dimorphic fungus existing as a mold in the soil (saprophytic stage) and as a yeast in tissues (parasitic stage). It causes systemic fu
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