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Define Effect of feeding method on drug availability?
The form in which a drug is administered or enters the body can influence its absorption, metabolism or excretion. This becomes more pronounced among critically ill patients who cannot consume drugs orally and are on enteral food support. If the drug has to be administered though the enteral feeding tube it needs to be either crushed or dissolved in a solvent. Crushing oral preparations to pass down the tube may alter their absorption time/activity.
Some of the drugs cannot be added to the food infusion as it may alter their stability. Several drugs are available only in the form of tablets or capsules, dissolving these in feed, water, alcohol or sorbitol may not always be feasible. Drug such as cimetidine, aluminium hydroxide, metaclorpromide are physically incompatible with enteral foods. Certain drugs like phenytoin form complexes with calcium and protein thereby resulting in markedly reduced absorption of this medication. Such drugs need to given only by stopping enteral feed infusions for 1-2 hours. Patients on total parenteral nutrition generally have a separate tube (catheter) for infusion of drugs. Toxicity/over dosage of drugs is frequently observed in case of certain drugs administered directly into the blood.
Q. Zonation in the ocean? The oceans play a major role in determining the climate and sustaining life on earth. Oceans help to redistribute the solar energy, through ocean curr
When the standard free energy of a reaction is -5.7 kj/mol then at equilibrium a- there will be 10 times more products than reactants b-there will be 10000 times more product
What can I do with this topic to make it into a brochure
Explain the Competitive behaviour of social animal group dominance behaviours removal of individuals to other groups which minimises inbreeding eg lions, apes.
Define the Causes of Failures of Root Canal Treatment 1. Errors in diagnosis and treatment planning 2. Coronal leakage ( inadequate restorative protection) 3. Lack of kno
how much classification of protozoa
A cat has just arrived to the veterinary clinic with low blood pressure. The cat weighs 5 kg, and as the on call Vet you want to use a bag of saline to prepare a dopamine drip for
How the Required weight gain Calculated? Weight gain is another aspect deserving attention. 'Allowable' or recommended weight gain could be higher than for adults. The weight g
In eukaryotes possibly the most rapid and complex signaling is mediated through nerve impulses. The Nerve cells (neurons) consist of a cell body with numerous projections
Q. Can you explain Lane and Eynon method? Reducing sugars are those, which have free sugar groups (e.g. glucose, fructose etc.) and hence may be estimated directly by titrat
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