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Define Effect of feeding method on drug availability?
The form in which a drug is administered or enters the body can influence its absorption, metabolism or excretion. This becomes more pronounced among critically ill patients who cannot consume drugs orally and are on enteral food support. If the drug has to be administered though the enteral feeding tube it needs to be either crushed or dissolved in a solvent. Crushing oral preparations to pass down the tube may alter their absorption time/activity.
Some of the drugs cannot be added to the food infusion as it may alter their stability. Several drugs are available only in the form of tablets or capsules, dissolving these in feed, water, alcohol or sorbitol may not always be feasible. Drug such as cimetidine, aluminium hydroxide, metaclorpromide are physically incompatible with enteral foods. Certain drugs like phenytoin form complexes with calcium and protein thereby resulting in markedly reduced absorption of this medication. Such drugs need to given only by stopping enteral feed infusions for 1-2 hours. Patients on total parenteral nutrition generally have a separate tube (catheter) for infusion of drugs. Toxicity/over dosage of drugs is frequently observed in case of certain drugs administered directly into the blood.
Insulin Syringe To administer Insulin properly, familiarize yourself with information about insulin: (a) insulin syringes, (b) storage, (c) site selection (d) steps for injecti
How I can optimize shake flask culture?
Following are the functions of Insulin: 1) Insulin controls the level of the sugar (glucose) in the blood. 2) Insulin permits cells to use sugar (glucose) for energy. Cells c
Nursing Education Computer-Assisted Instruction (CAI) is a valuable teaching aid for health care students, testing them with frequent quizzes to ensure that the material rea
Elaborate the term - Gill slits. Lateral opening in the wall of pharynx which allows water to enter into mouth and exit through the pharynx. This is one of the ancestral charac
Explain Procedure for Detection of Metanil Yellow? Carry out the exercise following the steps enumerated herewith. 1. Suspend the food sample in water and shake vigorously.
Q. Clinical Features of tricuspid regurgitation? Patients with severe primary tricuspid regurgitation will have symptoms of fatigue, dyspnoea and effort intolerance, abdominal
Why can the allantois be considered an adaptation to terrestrial life? The allantois is an adaptation to dry land because in embryos of oviparous terrestrial beings, like repti
What are some things that have algae in them? Yeast is considered Algae.
Why is the reaction of ethane and chlorine not a free-radical addition reaction? Because no free radicals are include in the reaction process only carbo cations and Cl- are evo
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