Define absorption, storage and elimination of vitamin k, Biology

Assignment Help:

Define Absorption, Storage and Elimination of Vitamin K?

Dietary vitamin K, mainly phylloquinone, is absorbed chemically unchanged from the proximal intestine after solubilization into mixed micelles composed of bile salts and the products of pancreatic lipolysis. In healthy adults, the efficiency of absorption of phylloquinone in its free form is about 80%. Within the intestinal mucosa, the vitamin is incorporated into chylomicrons, is secreted into the lymph, and enters the blood via the lacteals (minute intestinal lymph-carrying vessels). Once in the circulation,  phylloquinone is rapidly cleared at a rate consistent with its continuing association  with chylomicrons and the chylornicron remnants, which are produced by lipoprotein  lipase hydrolysis at the surface of capillary endothelial cells. Although phylloquinone is the major circulating form of vitamin K, MK-7 is also present in plasma, at lower concentrations and with a lipoprotein distribution similar to phylloquinone.

Vitamin K is stored in the liver - the site of synthesis of coagulation proteins -and of 90 percent menaquinones. Phylloquiucnes and menaquinones are also extra hepatic tissues. Phylloquinone levels are high in liver, heart and pancreas. Vitamin K is extensively metabolized in the liver and excreted in the urine and bile. About 60-70% of the amount of' phylloquinone absorbed from each meal will ultimately be lost to the body by excretion. This, therefore, suggests that the body stores of phylloquinone are being constantly replenished.


Related Discussions:- Define absorption, storage and elimination of vitamin k

Explain femoral approach, Q. Explain Femoral Approach? This approach in...

Q. Explain Femoral Approach? This approach involves the insertion of a catheter over a guidewire i.e. inserted into a sheath in the right femoral artery. Systemic anticoagulati

Cockroach - tracheal system, can you give brief diagram of the tracheal sys...

can you give brief diagram of the tracheal system of cockroach?

Explain energy requirement during tuberculosis, Explain Energy requirement ...

Explain Energy requirement during tuberculosis Energy  :  The criteria to establish  the energy intake is the body weight status coupled with the rise  in body temperature. Con

Define inadequate calcium intake and iron deficiency anaemia, Determine Eff...

Determine Effect of Inadequate calcium intake and iron deficiency anaemia? The requirement of iron and calcium is at its peak in adolescence due to an increase in the skeletal

What is osteogenesis, Osteogenesis The term osteogenesis describes esse...

Osteogenesis The term osteogenesis describes essentially two distinctly different phenomena by which bone can become juxtaposed to an implant surface.

What are the products and reagents of fermentation, Q. In general what are ...

Q. In general what are the products and reagents of fermentation? In fermentation glucose sugar is degraded into pyruvic acid each glucose molecule forms two pyruvic acid molec

What are the cells that produce the myelin sheath, What are the cells that ...

What are the cells that produce the myelin sheath? Of which substance is the myelin sheath formed? In the central nervous system (CNS) the myelin sheath is made by apposition o

State in brief about the nuclear dna, State in brief about the nuclear DNA ...

State in brief about the nuclear DNA The nuclear DNA is distributed between two or more chromosomes, the number of which varies among different eukaryotes, and is characterist

Zoology, type study of polystomella

type study of polystomella

The best absorbed in an acidic environment, Why is a weekly acidic drug bes...

Why is a weekly acidic drug best absorbed in an acidic environment?

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd