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Cyclosporine
Immunosuppressive agent that is selective for lymphocytes mainly "T" lymphocytes.
Route:
Oral, parental, dose as prescribed.
Side-effects:
Nephro-toxicity, systemic arterial hypertension, hyperkalemia, anaphylaxis if administered IV rapidly, hepatotxicity, lymphocytopenia, opportunistic infection, tremors. paraesthesia, muscle weakness, increased sensitivity to temperature changes.
Nursing implications:
Administer prescribed diuretics, antihypertensive. slow IV administration (over 4-6 hours), prevention of infection, breathing exercises, anti- fungal, monitor blood sugar, BP, peripheral edema, renal and liver function test.
Compare and contrast the effect of a deletion in the operator of the lactose operon with one in the operator of the histidine operon.
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