Cyclosporine, Biology

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Cyclosporine

Immunosuppressive agent that is selective for lymphocytes mainly "T" lymphocytes.

Route:

Oral, parental, dose as prescribed.

Side-effects:

Nephro-toxicity, systemic arterial hypertension, hyperkalemia, anaphylaxis if administered IV rapidly, hepatotxicity, lymphocytopenia, opportunistic infection, tremors. paraesthesia, muscle weakness, increased sensitivity to temperature changes.

Nursing implications:

Administer prescribed diuretics, antihypertensive. slow IV administration (over 4-6 hours), prevention of infection, breathing exercises, anti- fungal, monitor blood sugar, BP, peripheral edema, renal and liver function test.


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