Conversion of oxaloacetate to phosphoenolpyruvate, Science

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Conversion of oxaloacetate to phosphoenolpyruvate

Conversion of oxaloacetate to phosphoenolpyruvate: In this reaction, oxaloacetate and guanosine triphosphate (GTP) are converted to PEP, CO, and guanosine diphosphate (GDP). This reaction is catalyzed byphosphoenolpyruvate carboxykinase (PEPCK) which requires Mn⁺⁺ for its activation. In humans, this enzyme is equally distributed between mitochondria and the cytosol.

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