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The cell cycle is controlled by a cyclically operating set of reaction sequences that both trigger and coordinate key events in the cell cycle
• The cell-cycle control system is driven by a built-in clock that can be adjusted by external stimuli (chemical message).
• Checkpoint - a critical control point in the cell cycle where stop and go-ahead signals can regulate the cell cycle o Animal cells have built-in stop signals that halt the cell cycles and checkpoints until overridden by go-ahead signals. o Three Major checkpoints are found in the G1, G2, and M phases of the cell cycle.
• The G1 checkpoint - the Restriction Point o The G1 checkpoint ensures that the cell is large enough to divide, and that enough nutrients are available to support the resulting daughter cells. o If a cell receives a go-ahead signal at the G1 checkpoint, it will usually continue with the cell cycle o If the cell does not receive the go-ahead signal, it will exit the cell cycle and switch to a non-dividing state called G0 o Actually, most cells in the human body are in the G0 phase.
• The G2 checkpoint ensures that DNA replication in S phase has been completed successfully. • The metaphase checkpoint ensures that all of the chromosomes are attached to the mitotic spindle by a kinetochore.
What is Intra oral and Extra Oral A) Intra oral a) Frontal in occlusion b) Left and right occlusion (Using intra oral photography mirror) c) Occlusal view maxillary
HARD Y - WEINBERG LAW - Proposed by G.H. Hardy and W. Weinberg in 1908 independently. The law states "the frequency of genes or alleles in a population remains constant
Explain about Regenerative therapy Is also used to achieve the above objectives but with the ultimate goal of regeneration of lost bone tissue.
How do we Treat Protein Energy Malnutrition? Major objective of the treatment of PEM is to provide adequate energy and protein intake and control infections, if any. Mild and m
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Q. What are cerebrovascular accidents? The Cerebrovascular accident (CVA), as well known as stroke, is the generic name given to infarction (tissue and cellular death by hypoxi
Nerve to Mylohyoid Motor branch of inferior dental nerve which descends in a groove on the medial surface of the mandibular ramus. Surgical intervention in this area may lead
Protein Synthesis with DNA The central dogma of modern biochemistry is totally based on the coded information holded within deoxyribonucleic acid (DNA). Double stranded DNA is
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