Continual reassessment method, Advanced Statistics

Assignment Help:

Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic regression model for the dose-toxicity relationship and the prior distribution for the parameters. Once each patient's toxicity result becomes available posterior distribution of the parameters is recomputed and used to estimate probability of the toxicity at each of a series of dose levels.


Related Discussions:- Continual reassessment method

Cohort component method, Cohort component method : A broadly used method or...

Cohort component method : A broadly used method or technique of forecasting the age- and sex-speci?c population to the upcoming years, in which the initial population is strati?ed

Particlefilters, Particlefilters is a simulation method for tracking movin...

Particlefilters is a simulation method for tracking moving target distributions and for reducing computational burden of the dynamic Bayesian analysis. The method uses a Markov ch

Describe law of likelihood, Law of likelihood : Within framework of the sta...

Law of likelihood : Within framework of the statistical model, a particular set of data supports one statistical hypothesis or assumption better than another if the likelihood of t

Please answer this question, How large would the sample need to be if we ar...

How large would the sample need to be if we are to pick a 95% confidence level sample: (i) From a population of 70; (ii) From a population of 450; (iii) From a population of 1000;

Lipstick Dilemma, For a career woman, wearing lipstick has become an integr...

For a career woman, wearing lipstick has become an integral part of her daily life. It is not unusual for a woman to look for a lipstick that will stay on her lips and not smudge o

Probability., 5. Packages from a machine a normally distributed with a mean...

5. Packages from a machine a normally distributed with a mean 200g and its standard deviation 2grams. Find the probability that a package from the machine weighs a) Less than

Correspondence analysis, The method or technique for displaying the relatio...

The method or technique for displaying the relationships between categorical variables in a type of the scatter plot diagram. For two this type of variables displayed in the form o

Mareg, MAREG is the software package for the analysis of the marginal regr...

MAREG is the software package for the analysis of the marginal regression models. The package permits the application of generalized estimating equations and the maximum likelihoo

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd