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Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic regression model for the dose-toxicity relationship and the prior distribution for the parameters. Once each patient's toxicity result becomes available posterior distribution of the parameters is recomputed and used to estimate probability of the toxicity at each of a series of dose levels.
Persson Rootze ´n estimator is an estimator for the parameters in the normal distribution when the sample is truncated so that all the observations under some fixed value C are re
Matching distribution is a probability distribution which arises in the following manner. Suppose that the set of n subjects, numbered 1; . . . ; n respectively, are arranged in
A two-step distillation and mixing process is shown in the figure. The system operates at steady-state conditions and there are no chemical reactions. The known flow rates and comp
Interim analyses : An analysis made before the planned end of a clinical trial, typically with the aim of detecting the treatment differences at the early stage and thus preventing
Length-biased sampling : The bias which arises in the sampling scheme based on the visits of patient, when some individuals are more likely to be chosen than others simply because
a psychic claims to be able to "feel colors" there are three pieces of colored paper(red, blue,green) he will place his hand on radomly selected pieces while blindfolded. you perfo
Confidence profile method : A Bayesian approach to meta-analysis in which the information in each piece of the evidence is captured in the likelihood function which is then used al
Likert scales is often used in the studies of attitudes in which the raw scores are based on the graded alternative responses to each of a series of queries. For instance, the sub
1. You are interested in investigating if being above or below the median income (medloinc) impacts ACT means (act94) for schools. Complete the necessary steps to examine univariat
Genstat: The basic purpose piece of statistical software for the management and the analysis of data. The package incorporates the wide variety of data handling events and a wi
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