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Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic regression model for the dose-toxicity relationship and the prior distribution for the parameters. Once each patient's toxicity result becomes available posterior distribution of the parameters is recomputed and used to estimate probability of the toxicity at each of a series of dose levels.
The values assigned to factors for the individual sample units in a factor analysis. The most common approach is "regression method". When the factors are seen as the random variab
Kaiser's rule is the rule frequently used in the principal components analysis for selecting the suitable the number of components. When the components are derived from correlati
Lexis diagram is the diagram for displaying the simultaneous effects of the two time scales (generally age and calendar time) on a rate. For instance, mortality rates from cancer
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Nearest-neighbour methods are the methods of discriminant analysis are based on studying the training set subjects much similar to the subject to be classified. Classification mig
Linearity - Reasons for Screening Data Many of the technics of standard statistical analysis are based on the assumption that the relationship, if any, between variables is li
Probabilistic matching is a method developed to maximize the accuracy of the linkage decisions based on the level of agreement and disagreement among the identifiers on different
Normality - Reasons for Screening Data Prior to analyzing multivariate normality, one should consider univariate normality Histogram, Normal Q-Qplot (values on x axis
Chebyshev's inequality: A statement about the proportion of the observations which fall within some number of the standard deviations of the mean for any of the probability distri
Poisson regression In case of Poisson regression we use ηi = g(µi) = log(µi) and a variance V ar(Yi) = φµi. The case φ = 1 corresponds to standard Poisson model. Poisson regre
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