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Continual reassessment method: An approach which applies Bayesian inference for determining the maximum tolerated dose in a phase I trial. The method starts by assuming a logistic regression model for the dose-toxicity relationship and the prior distribution for the parameters. Once each patient's toxicity result becomes available posterior distribution of the parameters is recomputed and used to estimate probability of the toxicity at each of a series of dose levels.
Kappa coefficient : The chance corrected index of the agreement between, for instance, judgements and diagnoses made by the two raters. Calculated as the ratio of the noticed exces
For a career woman, wearing lipstick has become an integral part of her daily life. It is not unusual for a woman to look for a lipstick that will stay on her lips and not smudge
A manufacturing company has two factories F 1 and F 2 producing a certain commodity that is required at three retail outlets M 1 , M 2 and M 3 . Once produced, the commodity is
The marketing manager of Handy Foods Ltd. is concerned with the sales appeal of one of the company's present label for one of its products. Market research indicates that supermark
Treatment allocation ratio is the ratio of the number of subjects allocated to the two treatments in a clinical trial. The equal allocation is most usual in practice, but it might
how do you do this project
methods of determining trend in time series?
Multi co linearity is the term used in the regression analysis to indicate situations where the explanatory variables are related by a linear function, making the inference of the
Grade of membership model: This is the general distribution free method for the clustering of the multivariate data in which only categorical variables are included. The model ass
Briefly explain the importance of forecasting for managers?
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