Calculate the probability that both are carriers for tsd, Biology

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The male had a female first cousin (on his father side) who died from TSD and the female had a maternal uncle with TSD. Assume this trait is very rare.

1. Calculate the probability that both the femal and male are carriers for TSD?

2. What is the probability that neither of them is a carrier?

3. What is the probability that one of them is a carrier and the other is not?

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