Are fibrates effective at lowering tg levels, Biology

Assignment Help:

Q. Are Fibrates effective at lowering TG levels?

Fibrates are effective at lowering TG levels by 20 per cent to 50 per cent and raising HDL by 10-35 per cent. LDL reduction varies with the agent used and may range from 5 per cent-20 per cent in patients who are not hypertriglyceridemic. Although a higher mortality rate was seen in the clofibrate arm of the World Health Organization study, such a finding was not seen in subsequent studies of gemfibrozil or bezafibrate. These agents have been demonstrated to impart reduction in risk of CAD events and are of use to treat mixed hyperlipidemia. Although these agents are often used in combination with statin therapy, there are no studies demonstrating reduction in clinical events with this approach. This combination increase the risk of myopathy. For patients with very high TG levels, fibrate therapy reduces the risk for pancreatitis.


Related Discussions:- Are fibrates effective at lowering tg levels

Natural vegetative propagation, in natural vegetative propagation which st...

in natural vegetative propagation which structure gives rise to new individuals?

Light and distribution, Light and Distribution We have mentioned in the...

Light and Distribution We have mentioned in the beginning that the variation in the amount of light generally affects the global and local distribution of plants and animals. L

Hydrocele, Hydrocele A hydrocele is a painless water-filled cyst found...

Hydrocele A hydrocele is a painless water-filled cyst found in front of the testis.It is brightly translucent and cannot be emptied by pressure of a 'flap valve' at its jun

What are classes into which the phylum arthropoda is divide, Q. What are th...

Q. What are the classes into which the phylum Arthropoda is divided? What are the three major ones and some of their representative species? The three main classes of arthropod

Assessment of ventricular septal defect, Assessment   On assessment a c...

Assessment   On assessment a child with ventricular septal defect will show clinical manifestations depending upon the size of  the defect. The small defects are usually asympt

Explain food sources of lron, Explain Food Sources of lron? lron is fo...

Explain Food Sources of lron? lron is found in foods in one of the two forms i.e. haem or non-haem. In the human diet, the primary sources of haem iron are the haemoglobin and

Scentific american article suggests some improvements, The human skeleton h...

The human skeleton has evolved from that of four-legged animals. Unfortunately, the adaptation is far from perfect; thus, our upright posture causes problems like backage and the k

Calculate the width of the implant, Width of the Implant The width of t...

Width of the Implant The width of the implant especially at the interface area is critical towards the success of the implant. It has been recommended that at least 1mm of bone

Describe how platelets interact to form a blood clot, Describe briefly how...

Describe briefly how platelets, fibrin and red cells interact to form a blood clot.   Platelets release a substance which, indirectly, causes fibrinogen to be changed to fi

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd