Ablation experiment, Biology

Assignment Help:

Ablation experiment is an experiment designed to produce an animal deficient in one or the few cell types, in order to study cell lineage or the cell function. The logic is to make a transgenic mouse with a toxin gene (often known as diphtheria toxin) under control of a specialized promoter which activates only in the target cell type. When the embryo development progresses to the point where it starts to form the target tissue, the toxin gene is activated, and that particular tissue dies. Other tissues are not affected.


Related Discussions:- Ablation experiment

Intermediary metabolism, High Energy Compounds Primary need of the animal b...

High Energy Compounds Primary need of the animal body from the nutrients is energy. Free energy is the term used to denote the energy available to do useful work. Anabolic or synth

Explain the process of nucleotide catabolism, Question 1 Write a short not...

Question 1 Write a short note on the following Free Energy Cori cycle Fermentation Pentose phosphate pathway Transamination Allosteric Regulation Qu

Limb field, Limb Field By several marking and transplantation methods...

Limb Field By several marking and transplantation methods it is feasible to identify in early embryos the specific areas of groups of cells that ultimately make different org

Explain about the alitame - artificial sweeteners, Explain about the Alitam...

Explain about the Alitame - artificial sweeteners? Alitame (L-α-aspartyl-N-(2, 2, 4, 4-tetramethyl-3-thietanyl)-D-alaninamide), as illustrated in figure, is a sweetener based o

Show the process of cell-to-cell communication, On the overall process of c...

On the overall process of cell-to-cell communication within the nervous system, what role does the Ca2+ play in the synapse? A) contributes in the biosynthesis of acetylcholine B)

Explain about the qualitative tests for carbohydrates, Explain about the Qu...

Explain about the Qualitative Tests for Carbohydrates? This section will familiarize you with simple techniques and tests to identify carbohydrates in a laboratory. The objecti

Which type of ecological interaction is competition, Q. What is competition...

Q. What is competition? Which type of ecological interaction is competition? The Competition is the ecological interaction in which the individuals explore the similar ecologic

Explain techniques for broken instrument removal, Explain Techniques for Br...

Explain Techniques for Broken Instrument Removal Described by Gary Carr Staging platform (cutting in flat surface) a) Create straight line access to separated file using mod

Management of diabetes, By now you know that diabetes cannot be cured but c...

By now you know that diabetes cannot be cured but can be treated so that an individual leads a normal life. Patients who maintain their blood glucose levels within the normal range

Zoonoses disease- histoplamosis, Histoplamosis Caveran disease, darling’s ...

Histoplamosis Caveran disease, darling’s disease, reticuloendothelial cytomycosis or tingo maria fever are the other synonyms for histoplamosis caused by Histoplasma capsulatum. T

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd