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What is the value of ki for enalaprilat

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Reference no: EM131128568

Enalaprilat is a competitive inhibitor of the angiotensin-converting enzyme (ACE), which cleaves the blood-pressure regulating peptide angiotensin I.

ACE has a KM = 52 μM for angiotensin I, which is present in plasma at a concentration of 75 μM.

When enalaprilat is present at 2.4 nM, the activity of ACE in plasma is 10% of its uninhibited activity.

What is the value of KI for enalaprilat?

Reference no: EM131128568

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