Statements regarding fidelity of information transfer

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Reference no: EM133933393

Questions

1. Which one of the following statements regarding the fidelity of information transfer during DNA sequence to either DNA sequence or to RNA sequence to polypeptide sequence is INCORRECT?

a. A tRNA-bound elongation factor must stay on the ribosome during peptide bond formation.

b. In some cases, more than one codon can specify a specific amino acid.

c. Amino acid tRNA synthetases can catalyze the hydrolysis of a covalent bond linking amino acid to tRNA.

d. Mismatch repair requires DNA synthesis on just one strand of DNA.

2. Which one of the following statements concerning somatic mutations in cancer cells is INCORRECT?

a. A mutation in one allele of P53 can yield a protein product that blocks the function of the protein product of the other, unmutated allele.

b. Conversion of a normal cell into a cancer cell typically includes a combination of loss of a tumor suppressor gene function and a conversion of a proto-oncogene into an oncogene.

c. Conversion of a benign tumor into a malignant tumor is highly correlated with loss of p53 function.

d. Conversion of a proto-oncogene into an oncogene can only occur by mutations that change the amino acid sequence of the gene product.

Reference no: EM133933393

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