State what would be the charge of the imidazole side chain

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1) For the following question, assume the pKa of the alpha-carboxyl group = 2.0. What would be the charge of the alpha-carboxyl group of glycine at pH 7?

2) For the following question, assume the pKa of the alpha-carboxyl group = 2.0. What would be COOH:COO- ratio of the alpha-carboxyl group of glycine at pH 3?

3) For the following question, assume the pKa of the alpha-carboxyl group = 2.0. What would be the COOH:COO- ratio of the alpha-carboxyl group of glycine at pH 2?

4) For the following question, assume the pKa of the alpha-amino group = 10.0. What would be charge of the alpha-amino group of glycine at pH 12?

5) For the following question, assume the pKa of the alpha-amino group = 10.0. What would be the NH3+:NH2 ratio of the alpha-amino group of glycine at pH 9?

6) For the following question, assume the pKa of the alpha-amino group = 10.0. What would be charge of the alpha-amino group of glycine at pH 10?

7) What would be the charge of the imidazole side chain of histidine at pH 7? Assume the pKa of the side chain is 6.0.

8) Assume the pKa of the alpha-carboxyl group = 2.0 and the pKa of the alpha-amino group = 10.0. What would be the net charge of glycine at pH 6?

9) Assume the pKa of the alpha-carboxyl group = 2.0 and the pKa of the alpha-amino group = 10.0. What would be the net charge of glycine at pH 3?

10) Assume the pKa of the alpha-carboxyl group = 2.0 and the pKa of the alpha-amino group = 10.0. What would be the net charge of glycine at pH 9?

11) Assume the pKa of the alpha-carboxyl group = 2.0 and the pKa of the alpha-amino group = 10.0. What would be the net charge of aspartic acid at pH 9? Assume the pKa of the carboxyl side chain is 4.0.

12) Assume the pKa of the alpha-carboxyl group = 2.0 and the pKa of the alpha-amino group = 10.0. What would be the net charge of histidine at pH 3? Assume the pKa of the side chain is 6.0.

Reference no: EM13187691

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