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Professor Tipton, being an avid hunter, was stalking the woods for morels. He saw a giant morel next to a fallen tree. When he reached down to get it a small timber rattler bit his hand. By time he got back to the car, the bite mark was swollen and extremely painful. Being a card-carrying enzymologist, he knew that many snake venoms contain phospholipases A2. a) Explain why the snake bite caused rapid pain and inflammation (a biochemical explanation; it has nothing to do with Dr. TiptonTMs pain tolerance). b) Based on your biochemical understanding of the mechanism of the pain (Chapter 10), suggest a possible treatment (no amputations please). c) If too much phospholipase A2 enters the bloodstream, the significant accumulation of one of the products of the reaction acts as a powerful detergent, causing the lysis of red blood cells and potential death. What is this dangerous product and what makes it such a good detergent?
Melittin is a 26 amino acid helical peptide (GIGAVLKVLTTGLPALISWIKRKRQQ) that is the major component of bee venom and is responsible for cell death by disrupting the plasma membrane. Develop a logical explanation of how this peptide could facilitate membrane disruption.
A sample of neon gas used in a neon sign occupies a volume of 1.50 L at a pressure of 630 torr. Calculate the volume of the gas if the pressure in the glass tube of the sign is 793 torr.
what solution will have the lowest boiling point?
A hydrogen-filled balloon was ignited and 2.00 gram of hyrdogen reacted with 16.0 g of oxygen. How many grams of water vapor were formed?
Express your answer to three significant figures and include the appropriate units. 0.037 Correct Part B What pressure is required to achieve a concentration of 7.10×10?2 at 20?
A 4.78 L sample of H2O(g) reacts at a temperature of 375°C and a pressure of 692 mm Hg. How many grams of NH3 can be produced?
Find what is the initial concentration of the chlorine before dilution - unknown concentrated chlorine
A sample of iron was dissolved iin hydrochloric acid. The liberated hydrogen was collected by displacement of water. The hydrogen occupied 262 mL at 26 c.
you perform a titration between a solution of ammonium (Kb = 1.8*10^-5) and HCL. you have a 200 ml of 50.0mM ammonium solution titrated against
Draw a reaction coordinate diagram for each of the following nucleophilic addition-elimination reactions. a. the nucleophile being a weaker base than the leaving group
What is the number of moles of O2 needed to burn 260.0g of C2H2 in the reaction: 2C2H2 + 5O2 yields 4CO2 + 2H2O?
calculate the potential of a platinium electrode immersed in a solution prepared by mixing 25.00ml of 0.0918 M SnCl2
A mixture of CO, CO2 and O2 is contained within a 275 mL flask at 0C. If the total pres- sure is 780 torr, the CO has a partial pressure of 330 torr and the CO2 has a partial pressure of 330 torr, what is the partial pressure of O2?
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