State elution order of the two compounds in capillary

Reference no: EM13171874

1 Aspirin has a pKa of 3.5 and is neutral in its protonated form (i.e. HA). Acetaminophen has a pKa of 9.5 and is also neutral in its protonated form. Predict the elution order of the two compounds in capillary electrophoresis. Assume electroosmotic flow (EOF) is present and that the detector is at the negative end of the capillary.

(a) pH = 3.0
(b) pH = 6.0
(c) pH = 9.0
(d) pH = 12.0

2. What is the main drawback of electrokinetic injection? (one sentence)

3. Draw the van Deemter curve for a capillary electrophoresis experiment.

Reference no: EM13171874

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