Standard screening test for the down syndrome

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The standard screening test for Down's Syndrome is based on combination of maternal age and the level of serum alpha-fetoprotein. Using this test 80% of Down's syndrome cases can be identified, while 5 % of normals are detected as positive.

What is the sensitivity and specificity of the test?

Suppose that 1 out of 500 infant's are born with Down's Syndrome.

Reference no: EM1395120

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