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A mutation in the Ras protein renders Ras constitutively active(RasD). What is constitutive activation? How isconstitutively active Ras cancer promoting? What type of mutationmight render the following proteins constitutively active: (a)Smad3; (b) MAP kinase
Describe the role of ubiquitin in mediating intracellular protein breakdown.This description must include a description of the ubiquitination pathway?
A plasmid digest with BamHI produced 2 kb and 4 kb fragments. Digest of a plasmid with HindIII produced 6 kb fragment. Double digest with both enzymes produced 1 kb, 2 kb and 3 kb fragments. Sketch a plasmid map.
The genes ABCD are on the same chromosome but not necessarily in this order. The crossover frequencies between genes, in map units, are A to B=6, A to C=5, C to D=3, B to C = 11, B to D = 14. What is the correct order of these genes on the chromos..
What are satellite colonies? Why can satellite colonies be formed? If you use an antibiotics such as tetracycline, will you even get satellite colonies and why?
Black coat of animal is dominant; white is the alternative recessive. While true-breeding black is crossed to true-breeding white, what is the possibility that a black F2 is heterozygous.
Why is it beneficial to plants that soil particles have negatively charged surfaces.
What effect do you think EBV would have on B cell function. What phenotypes would you expect in the F2, and in what actual numbers (not ratios) will you expect to find out them.
Suppose the gene for dimples, d, is recessive. Then suppose that two individuals with the genotypes Dd and dd mate.
describe in-depth an ecological issue including at least two different perspectives and how this issue is
How many times more likely is the offspring of a cousin mating to suffer its effects (that is, to be homozygous for it) than is an outbred individual?
Although each of the following has a better chance of influencing gene frequencies in small populations than in large populations, which one most consistently requires a small population as a precondition for its occurrence?
Estimate the consequence of a DNA mutation, within the first exon of a gene, that results in a change from TAT, which codes for Tyrosine, to TAA?
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