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Discuss what you would require to know to answer the following question: of all proteins that exist on earth at this time, what fraction of them have a known structure? Take into consideration that many proteins in an organism are splice variants and that mutations of the wild type can occur in individuals. Also, do you think it is now, or would it ever be, possible to answer this question, and what would have to be done to get the answer? Can an estimation be made, and what factors would need to be estimated?
Consider the HIV enzyme called protease. The amino acid residues at the active site are highly hydrophobic. In designing a drug that would bind to the active site and jam it, researchers should use which sort of molecule.
Illustrate what is meant by motivation. What types of non-financial reward might a company employ to motivate employees.
Though the bone was properly set, by the time boy was 16 it was apparent that the injured lower limb was shorter than normal one. Elucidate why this difference occurred. What caused her symptoms? Was her condition because of an infection or intoxicat..
What kind of measure is useful in investigating the epidemics? Enlist the steps you would carry out for detecting or investigating an outbreak.
In a donor population, the allele frequencies for the normal and the sickle-cell allele are 0.9 and 0.1 respectively. A group of 55 individuals migrates to population containing 10,000 individuals.
When cloning a gene into an expression vector, people frequently use two different restriction enzymes so that passenger DNA can be inserted in the correct orientation with respect to promoter sequence present in the plasmid. But orientation is almos..
how to Calculate the fraction of Vmax. For an enzyme which obeys Henri-Michaelis-Menten kinetics.
When a sperm cell comes into contact with an egg cell, there is a change in the electrical charge across plasma membrane and various channel proteins close. What are these channels known as.
Suppose the diameter of the field of vision in your microscope is 2mm under low power. If one Bacillus cell is 2 micrometers how many Bacillus cells could fit end to end across the microscope? How various 10 micrometers yeast cells could fit across t..
Trace path from the femoral vein in a healthy female to the lower lobe of the right lung via the right pulmonary artery. Explain all major structures on the way.
Using these data, estimate the density (number/hectare) of each size class plus the overall density. [Note: 1 hectare = 10,000 m 2 .]
The genes dumpy wings, clot eyes, and apterous wings are linked on chromosome II of Drosophila. In a series of two-point mapping crosses, the genetic distances demonstrate below were determined.
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