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In class, we discussed how H146 of the β-chain of normal adult hemoglobin ends up in close proximity to D94 on the same chain when oxygen is delivered to the tissues. In hemoglobin Hiroshima, however, H146 on the β-chain has been changed to a D through mutation.
a) What effect, if any, does this mutation have on oxygen binding by hemoglobin Hiroshima, compared to normal hemoglobin? Explain. Hb Hiroshima will bind O2 easier. (You explain why).
b) What effect, if any, does this mutation have on the Bohr Effect of this mutant hemoglobin? Explain. This mutation will weaken the H+ portion of the Bohr effect, but will have no consequence on the CO2 portion of the Bohr Effect. (You explain why for both).
It is a very curcial concept to understand how the immune response is mounted against viruses, bacteria, protozoans and helminthes. For an effective immune response, both innate and adaptive immunity should work together.
This Project report elaborates a critical review of important elements attached to Advanced Glycated End Products (AGEs). It is very crucial to understand the process called Millard reaction.
Soil stabilization is the permanent physical and chemical alteration of soils to enhance their physical properties. Stabilization can increase the shear strength of a soil and control the shrink-swell properties.
This assignment has three parts which contains questions related to Microbiology. It contains basic principles of microscopy, staining techniques in microbiology and microbial growth in the food industry.
Lipid metabolites are often seen as key elements in cellular signaling. Is this unique? Please provide several examples of the function of lipids as key elements in signal arrays and list the biologic functions these signals affect?
Please describe how one might search for chemical structure, biologic function relationships, involving small molecular weight lipophylic compounds. Provide one example.
Write a case study which detailing a scenario of a patient being investigated in the Haematology laboratory.
The use of PCR and genetic approaches in biotechnology
Glucose oxidase is an enzyme that can be used for measurements of glucose levels by combining this reaction with an oxygen probe.
What phenotypic ratio would you get if you crossed a white mouse and a heterozygous brown mouse?
Prepare an essay on nosocomial infection.
To increase the awareness of monitoring and recording the blood pressure of patients and practice measuring blood pressure in a safe environment.
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