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The following data were collected in a clinical trial evaluating a new compound designed to improve wound healing in trauma patients. The new compound is compared against a placebo. After treatment for 5 days with the new compound or placebo the extent of wound healing is measured and the data are shown below.
Percent Wound Healing
Treatment
0-25%
26-50%
51-75%
76-100%
New Compound (n=125)
15
37
32
41
Placebo (n=125)
36
45
34
10
Is there a difference in the extent of wound healing by treatment? (Hint: Are treatment and the percent wound healing independent?) Run the appropriate test at a 5% level of significance.
df= ________
alpha= ________
Reject H0 if ?2>________
Compute expected frequencies
Expected Frequency = (Row Total * Column Total)/N.
Complete the expected frequencies for each cell.
Total
New Compound
( )
125
Placebo
51
82
66
250
Compute ?2.
?2= ________
Based on comparing the computed ?2 to the rejection level ?2 which of the following is (are) true?
A. We have statistically significant evidence at alpha=0.05 to show that H0 is false.
B. Treatment and percent wound healing are not independent.
C. Treatment and percent wound healing are independent.
D. a and b.
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