Already have an account? Get multiple benefits of using own account!
Login in your account..!
Remember me
Don't have an account? Create your account in less than a minutes,
Forgot password? how can I recover my password now!
Enter right registered email to receive password!
Question: Scientists were able to show that CML was caused solely by the over expression of the Bcr-cAbl protein kinase and tested 400 small molecules until they found a highly specific kinase inhibitor. This drug was then tested in clinical trials and shown to cause remission in more the 90% of CML patients as long as the drug was taken daily. Why is the specificity important for the success of this drug?
Select one:a. There are fewer side effects if the drug is only inhibiting growth of cells expressing the Bcr-cAbl protein kinase rather than all growing cells (like most chemotherapy).b. If it were a non-specific inhibitor of all protein kinases, it would be highly toxic as there are many essential protein kinases.c. A and B.
What SARS viral proteins are made using the frameshifting? Is there only one SARS viral protein made using frameshifting or are there many proteins made using frameshifting?
The four phases of the disposition of a toxic compound to assess its toxicity are absorption by membranes in a system, the distribution throughout the system.
At puberty, the adolescent female body changes in both structure and function of several organ systems, primarily under an influence of changing concentrations of estrogen and other steroid hormones. How can one hormone, such as estrogen, mediate so ..
At the end of the measurement period, which group will have produced the greatest volume of urine and which group the minimum? Describe your answer in details.
Explain about the cell wall and nucleoid of bacterial cell, their structure and composition in detail. Explain the functions of the sensory neurons, interneurons, and motor neurons in the nervous system in brief.
The measurements to be comparable in both preparations. Illustrate one experiment you could perform to demonstrate such lack of equivalence of the two cells in the zygote. Noticeably state the expected outcome of your experiment in the reply you prov..
Use the I/v curves for leak and INa describe how the treshold of an action potential can be dtermined and the peak height.
Given blood spatter patterns, is possible to estimate the direction the blood was traveling, angle of impact, and the point.
In horse, black coat colour is influenced by the dominant allele (B) and chestnut coat colour by the recessive colour (b). Trotting gait is due to dominant gene (T), pacing gait to the recessive allele (t). What colour horse would you use to find out..
Trace path from the femoral vein in a healthy female to the lower lobe of the right lung via the right pulmonary artery. Explain all major structures on the way.
Assume your professor handed you a test tube with 3.0 ml of an E.coli culture in it and told you to make a 10^(-3) dilution of the entire culture. Describe how you would do it.
When Purified Protein Derivative (PPD) isolated from Mycobacterium tuberculosis was injected into the skin of a patient, it caused an area of hardening 1 cm in diameter. How must this PPD test be interpreted? What caused the result.
Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!
whatsapp: +1-415-670-9521
Phone: +1-415-670-9521
Email: [email protected]
All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd