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Sialic acid-rich glycoproteins are important components of mammalian cells. They are used by host cells to bind molecules on other cells. In addition, sialic acid moitites can be shed and accumulate around cells or in the extracellular fluid where they act as decoys for pathogen binding. Several pathogens, some bacteria and a few viruses, have evolved virulence factors that utilize sialic acid to their benefit. Propose two reasonable mechanisms for bacteria and or viruses to utilize host cell sialic acid or sialic acid-rich glycoproteins as virulence factors. Don't just list them, describe your ideas and discuss the benefit to the pathogen for each mechanism you propose
Compared to impact craters on other moons, young impact craters on Europa (including the Pwyll impact crater) show a distinct absence of high crater walls, or any significant depression towards the center. What does this suggest about Europa's icy..
Using the Enterotube II system and the interpretation guide, explain why don't you poke a hole into the plastic covering the glucose compartment? Explain. What does it mean if the wax pulls away from the agar?
How is a Scathard plot generated, and what measure of the inter-molecular interaction is used to find this?What is the proteasome.
All of the following illustrate why the bile acids are much better suited then cholesterol for use as emulsification agents for fats except.
When is double strand break repair important in bacteria? What about eukaryotes? (in other words, what are the situations when you would expect to get ds DNA breaks in each type of organism?)
How would the research programs of the two schools have influenced their perceptions about the amount of genetic variation present in the wild?
A groom's sister has CF, an autosomal recessive disease, though he himself does not have nor do either of his parents. He is marrying a woman with no family history of CF.
What phenotypes would you expect in the F2, and in what actual numbers (not ratios) would you be expecting to find them. Describe the process of speciation. Comprise in the discussion the factors that can contribute to the maintenance of genetic isol..
You need to load 10 ug of protein into one of the wells of a gel. This needs to be in 1x buffer and in a total volume of 15 uL. You are given a 10 ug/uL solution of protein, a 5x buffer, and water. How much of each should you mix to load the gel c..
Determine which do you think would have the most serious effect, and why: a 5 mEq/L increase in the plasma concentration of sodium, potassium, chloride, or calcium?
explain the molecular basis for the adage: "Fats burn in the flame of carbohydrates" in other words, why is fatty acid catabolism dependent on an adequate supply of carbohydrates in our diet?
q.a. what is gmas position on obesity?b. what causes obesity?c. what is gma doing in the fight against obesity?d. after
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