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Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting the production of the enzyme 21-hydroxylase, which is coded for on chromosome 6. One of the effects of having a defect in 21-hydroxylase function is the inability to break down testosterone. This leads to high levels of the hormone. Female fetuses exposed to high levels of testosterone during development can be born with ambiguous genitalia.
Neither Jason nor Jenny were affected by CAH, but their daughter Emily was. Jason and Jenny are now expecting a set of fraternal (non-identical) triplets. What is the chance that ALL the babies will also have CAH? How would you show this using a punnet square?
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