Homeostasis of alzheimer disease

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Question: Metal ions affect the homeostasis of Alzheimer's disease (AD) patients. Khanahmadi et al. conducted a study to compare the metal ions iron, zinc and copper in patients with AD with the normal range provided by the laboratory. Among a group of 17 patients with AD in Tehran's aging centers in 2015, blood samples were collected and analyzed for iron, zinc and copper in a pathobiological laboratory. Results are provided in the table below (units are in μg/dL).

Metal Ion n Sample Mean Standard Error Normal Range

Iron 17 55.76 4.75 37-145

Zinc 17 64.35 3.27 80-120

Copper 17 119.29 5.61 80-155

Using a 0.01 significance level, you need to test the claim that this sample comes from a population with a mean zinc level that is significantly less than 80 μg/dL (i.e., the lower limit of the normal range).

1) What is the value of the test statistic you should use to test the given hypothesis? a. -1.16 b. -1.75 c. -1.96 d. -4.79 e. -19.73 

2) If you were told that the population standard deviation was 13.5, what critical value would you use to test the given hypothesis?

a. -2.921

b. -2.583

c. -2.576

d. -2.567

e. -2.326

f. None of the above because we need 2 critical values (one positive and one negative)

Reference no: EM132157670

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