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Question: Cystic fibrosis (CF) is a genetic disease that leads to formation of thickened mucus in the lungs, pancrease, and other organs. In the lungs, the mucus impeads airflow and the removal of particulates leading to infection. These problems result in a decreased lifespan for those with CF.Most people with CF have a mutation in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene that results in the deletion of the amino acid phenylalanine at position 508 in the primary sequence of the protein (F508del-CFTR).What types of forces/bonds would likely be disrupted by the deletion of phenylalanine?
Question: Normal CFTR is a transmembrane protein that functions as a chloride channel in the plasma membrane. The mutant protein (F508del-CFTR) does not fold properly, because key molecular contacts are missing due to the absence of phenylalanine 508. Patients homozygous for the F508del-CFTR mutation do not express any normal CFTR. CF patients express the mutant F508del-CFTR protein, but only a very small amount is found in the plasma membrane.In which subcellular organelles/locations would you expect to find the mutant F508del-CFTR protein? (you may choose more than one answer)cytoplasm b mitochondria c rough ER d golgi e chloroplast f lysosome
Two plants in a cross were each heterozygous for two gene pairs whose loci are linked and twenty-five mu apart. Assuming that crossing over occurs during formation of both male and female gametes
A marine biologist has dredged up an unknown animal from the seafloor. Describe some of the characteristics she must look at to determine the phylum to which the animal have to be assigned.
A researcher wants to develop a test that will distinguish charophytes and land plants from green algae. Which chemicals would be the best subject for such an assay.
Diplomonads, such as Giardia contain two haploid nuclei per trophozoite. Thus, During the G1 phase of the cell cycle, there should be a total of how several unreplicated chromosomes per trophozoite, and throughout the G2 phase, how many replicated ch..
How is geological energy different from biological energy. Charlie has the blood test that shows a normal level of LDLs other than an elevated level of HDLs in his blood. Because his family has a history of cardiovascular disease, he wonders if he mu..
Determine which of the following in an enzyme that is involved in both cell cycle control and DNA repair?
Explain the processes involved in cellular protein synthesis. How would synthesis be affected by intake of an otherwise adequate diet that is very low in glycine or low in tryptophan?
Lack's model for clutch size evolution forecast the optimal number of offspring in a clutch as those which produce the most offspring.
Think about the sequence 3'-T-C-T-C-T-A-C-G-T-5' and calculate the total number of covalent bonds joining the nucleotides in each strand?
Carbonate precipitation can occur due to biological activities. Algal carbonate precipitation is relatively well known.
On the other hand, vascular plants became dominant during the invasion of what type of habitat? What structures allowed them to infiltrate this new environment.
The Verhulst's logistic model has been practical to the natural growth of the halibut population in certain areas of the Pacific Ocean. Let NN, measured in kg, be the total mass (or biomass) of the halibut population at time tt.
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