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Question: Suppose You want to add PMA to 15mL of HL-60 cells so that you have a concentration of 5nM. Your stock solution is 1uM. What is the volume of the stock solution you need?
Question: The molecular weight of vincristine, a pharmaceutical drug, is 923.04. It is supplied in 1 mg per vial. You want to treat your culture cells with a final concentration of 2.5nM vincristine and will need 5mL of cells for your experiment. You only want to add 2uL of vincristine solution to your cells. What concentration should you make your stock solution of vincristine in order to make this 2uL addition?
If the preclinical prevalence of breast cancer increased in the screened population would you expect the positive predictive value to increase, decrease or remain unaltered? Why?
Compute the allelic and genotypic frequencies for the disease assuming Hardy?Weinberg equilibrium. Show your work and express your answer to three significant figures.
An assured drug that is used to control high blood pressure stimulates K+ excretion in the kidney such that plasma [K+] decreases from a normal value of 5 mM to 2.5 mM. Intracellular [K+] is largely unaffected. What effect this drug will have on the ..
In parrots, language spoken is determined through one gene, and the allele, N, for Norwegian, is completely dominant to n, Danish.
The structure of a mammalian hormone oxtocin, a nine-amino acid polypeptide as follows: cys-tur-ile-glan-asn-cys-pro-leu-gly. At the carboxyl end, the -OH is replaced by an amino group.
Why the parents wake up, other than the children did didn't wake up. A gene for sweat gland production is found on the X chromosome.
Give a functional definition of a eukaryotic gene. Please include all parts of a eukaryotic gene and what the function of each element is.what are a lytic and a lysogenic bacteriophage.
Assume you examine the stability of your favorite protein kinase and find that half of the protein is degraded every 10 minutes.
In the year following the fires, wildflowers sprouted in all burned areas, closely followed in subsequent years by seedlings of the trees that normally grow in the area, such as aspens and lodge poles pines. What changes in the Ecosystem will take pl..
In order for the 4-nitrophenol to release the yellow colour expected, it has to be fully ionised. With a pKa of 7, I have decided that pH9 will allow it to be fully ionised - this is also supported by yellow colour given off, and a reasonable calib..
Analyze the contributions of select scientists from the Greek and Roman period. Explain the Arab influence on the development of anatomy and physiology.
What would happen to heart rate and peripheral resistance? Would it be probable to build a working circuit without the inhibitory interneuron? If so, how would you do it? If not, why can't you do it.
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