Figure similar to one of figures that illustrates case study

Reference no: EM131411627

Refer to given Case Study, in which physicians were randomly assigned to take aspirin or a placebo, and heart attack rates were compared. Draw a figure similar to one of Figures that illustrates the steps for Case Study.

1691_Fig 1.jpg

Case Study
Does Aspirin Reduce Heart Attack Rates?
In 1988, the Steering Committee of the Physicians' Health Study Research Group released the results of a 5-year randomized experiment conducted using 22,071 male physicians between the ages of 40 and 84. The purpose of the experiment was to determine whether or not taking aspirin reduces the risk of a heart attack. The physicians had been randomly assigned to one of the two treatment groups. One group took an ordinary aspirin tablet every other day, while the other group took a placebo. None of the physicians knew whether he was taking the actual aspirin or the placebo. The results, shown in given Table, support the conclusion that taking aspirin does indeed help to reduce the risk of having a heart attack. The rate of heart attacks in the group taking aspirin was only about half the rate of heart attacks in the placebo group. In the aspirin group, there were 9.42 heart attacks per 1000 participating doctors, while in the placebo group, there were 17.13 heart attacks per 1000 participants.

Table: The effect of Aspirin on Heart Attacks
Treatment	Heart Attacks	Doctors in Group	Attacks per 1000 Doctors
Aspirin	104	11,037	9.42
Placebo	189	11,034	17.13

Because the men in this experiment were randomly assigned to the two conditions, other important risk factors such as age, amount of exercise, and dietary habits should have been similar for the two groups. The only important difference between the two groups should have been whether they took aspirin or a placebo. This makes it possible to conclude that taking aspirin actually caused the lower rate of heart attacks for that group. In a later chapter, you will learn how to determine that the difference seen in this sample is statistically significant. In other words, the observed sample difference probably reflects a true difference within the population. To what population does the conclusion of this study apply? The participants were all male physicians, so the conclusion that aspirin reduces the risk of a heart attack may not hold for the general population of men. No women were included, so the conclusion may not apply to women at all. More recent evidence, however, has provided additional support for the benefit of aspirin in broader populations.

Moral of the Story: Unlike with observational studies, cause-and-effect conclusions can generally be made on the basis of randomized experiments.

Definitions: A randomized experiment is a study in which treatments are randomly assigned to participants. A treatment is a specific regimen or procedure assigned to participants by the experimenter. A random assignment is one in which each participant has a specified probability of being assigned to each treatment. A placebo is a pill or treatment designed to look just like the active treatment but with no active ingredients. A statistically significant relationship or difference is one that is large enough to be unlikely to have occurred in the sample if there was no relationship or difference in the population.

Reference no: EM131411627

Questions Cloud

Describe briefly the software package called pgp : State four reasons why physical security is needed. Discuss briefly the benefits and limitations of asymmetric key encryption. Explain briefly the fivesteps undertaken in risk analysis.Describe the procedure involved in automatic password cracking al..

Describe the risks and benefits of your two choices : Suppose you need $1 million dollars to start your Dream Business. Research ways to get the money for such a business. Compare two sources of financing you might obtain. Identify the risks and benefits of your two choices.

Npv using a variety of risk adjusted discount rates : Compute the new NPV using a variety of risk adjusted discount rates. Justify your computations in determining how you have adjusted discount rates for risk.

What is the probability that it is a corner item : We have n3 items arranged in the form of a lattice in a cube, and we pick at random an item from an edge (not on the bottom). What is the probability that it is a corner item?

Figure similar to one of figures that illustrates case study : Refer to given Case Study, in which physicians were randomly assigned to take aspirin or a placebo, and heart attack rates were compared. Draw a figure similar to one of Figures that illustrates the steps for Case Study.

What should be the relation between target capital structure : What should be the relation between the target capital structure for a firm and the firmâ€TMs optimum capital structure? Which of the following is a correct way to calculate degree of combined leverage?

Examine the results that were attained by disney : Write a two to four (2-4) page paper in which you: Describe the reasons for Disney's adoption of ITIL. Examine the results that were attained by Disney

Formal and informal structure within an organization : Describe the formal and the informal structure within an organization. Describe the characteristics of a work based team including the advantages and disadvantages. You have been placed in charge of a health care department. Describe how you might go..

Find a way to be unique and to add value by bundling service : Explain what factors you used in choosing your specific marketing strategies and the purpose of each selection. Find a way to be unique and to add value by bundling services.

User Account

All Pages