Explain the predicted effect on glycine biosynthesis

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Describe the predicted effect on glycine biosynthesis in a mutant mammalian cell if there is a mutation in the 5'-IRE sequence of ferritin mRNA that reduces the Ka of IRP binding as compared t binding with wild-type mRNA. You can assume RNA Pol II is unaffected by this mutation. A biochemically correct explanation in support of your prediction is required, and where necessary, provide the affected biosynthesis pathways to support your prediction

Reference no: EM13208306

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