Explain the pka of a glutamic acid side change

Reference no: EM13190331

Tuning proton affinity. The pKa of an acid depends part,y on its environment. Predict the effect of each of the following environmental changes on the pKa of a glutamic acid side change.

(a) A lysine side chain is brought into proximity.

(b) The terminal carboxyl group of the protein is brought into proximity.

Reference no: EM13190331

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