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Question- You will find below the catalytic triad of chymotrypsin, along with a peptide located in the substrate-binding site of the enzyme. Provide a detailed answer to the following questions
Part- a) Explain how the enzyme recognizes the correct amino acid side chain located next to the peptide bond to be cleaved;
Part- b) Explain how the enzyme recognizes the correct peptide bond to cleave (i.e. N- vs C-terminal side of the target amino acid);
Part- c) Explain each of the steps leading to the cleavage of the peptide bond.
NOTE- You don't have to show how the enzyme is regenerated.
I need expert help to solve the above question. Show each and every step.
The most probable mechanism of reactivity for the solvoysis of 2-chloro-norbornane is: a. Sn1 b. Sn2 c. E1 d. E2 The reaction for this secondary compound was very slow going compared to solvolysis of benzyl chloride
Each was extracted with three 5-mL aliquots of CCl4 containing an excess of 8-hydroxyquinoline. The extracts were diluted to 25 mL and their fluorescence was measured. What is the concentration of the zinc in the unknown solution Volume of Zn sta..
Claculate the potential for this cell, Ecell, at 25 degree Celsius. Can a reaction be spontaneous at 298 K when its delta Grxn (298 K) is positive
In an electron microscope the electrons generate the image. For one of the scanning electron microscopes in our Central Analytical Facility, the electrons are accelerated to have a kinetic energy of 200,000 eV.
For the subsequent reactions, look up the delta Hf values to compute delta H rxn and S values to evaluate delta S system and hence compute delta S universe at 298 K.
For the following reaction, 5.43 grams of potassium hydroxide are mixed with excess carbon dioxide. The reaction yields 6.09 grams of potassium carbonate.
A chemist needs to determine the concentration of a solution of nitric acid HNO3, She puts 865mL of the acid in a flask along with a few drops of indicator. She then slowly adds 0.600M Ba(OH)2 to the flask until the solution turns pink, indicating..
Please complete and balance the molecular equation and write a net ionic equation, make sure to include the physical states of the compounds, if there is not reaction write NR for the products.
a student combusts 504.96 grams of ethene gas c2h4. how many liters of co2 g are produced at a pressure of 0.993 atm
What is the pH of a buffer that consists of 0.20 M NaH2PO4 and 0.40 M Na2HPO4? Ka = 6.2 × 10-8
Write balanced (a) molecular, (b) overall ionic, and (c) net ionic equations for the reaction between an aqueous solution of phosphoric acid, H3PO4(aq), and an aqueous solution of sodium hydroxide. The products are sodium phosphate and water.
What is the freezing point of a solution that contains 23.0g of urea, CO(NH2)2, in 275mL water, H2O. Assume a density of water of 1.00 g/mL
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