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Evaluate the ratio of ionized to unionized drug forms

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The OTC antihistamine chlorpheniramine maleate is a cationic acid with an unionized conjugate base and a pKa of 9.4. Calculate the ratio of ionized to unionized drug forms that would exist in the plasma at physiological pH (7.4). What is the percent ionized to unionized?

Reference no: EM13546264

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