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Question - Toll-like receptors (TLRs) are immunoreceptors responsible for the detection of pathogen-derived molecules. Human TLR4 is a membrane protein with an N-terminal extracellular domain and a C-terminal cytosolic domain connected by a single transmembrane a-helix. The sequence of the transmembrane helix is IIGVSVLSVLVVSVVAVLVY. Estimate the thickness of the cell membrane according to structural features of the a-helix. Draw a simple cartoon figure of TLR4 with the a-helix embedded in the membrane and explain why this a-helix is rich of hydrophobic residues. (The cartoon of the a-helix should show the correct length and handedness of the a-helix).
What is the ph of a solution that is the mixture of 0.008 M of NaOAc and 0.1 M HOAc? (Ka HOAc= 1.8 x 10^-5)
Explain how molecular spectroscopy can be used for either the measurement or identification of a molecule.
Classify the solid state of the following substances as ionic crystals, covalent crystals, molecular crystals or metallic crystals: (a) CO2 (b) B12 (c) S8 (d) KBr (e) Mg (f) SiO2 (g) LiCl (h) Cr
consider the following ksp values for metal sul?desmgc2o4 8.6 times 10-5coc2o4 2.7 times 10-9cuc2o4 2.9 times
The volume of a sample of gas, initially at 25oC, increase from 158 ml to 450 ml. What is the final temperature (C) if the pressure in the container is kept constant.
What temperature T2, in Celsius, is needed to reach this pressure. Express the temperature numerically in degrees Celsius.
An ice bag containing 212g of ice at 0 °C was used to treat sore muscles. When the bag was removed, the ice had melted and the liquid water had a temperature of 32.5°C.How many kilojoules of heat were absorbed?
What is the difference between a straight-chain and branched-chain alkane? What is the difference between an alkane and an alkyl group?
Calculate the partial pressure of hydrogen gas at equilibrium. and calculate the vaue of Kp for this reaction.
If 29.58 mL of 0.550 M NaOH is required to titrate the oxalic acid in the 0.554g sample to the equivalence point, what is the weight percent of oxalic acid in the mixture. Oxalic acid and NaOH react according to the equation H2C2O4 (aq) + 2 NaOH(a..
Determine the molarity of a solution made by dissolving 20.0 g of NaOH in sufficient water to yield 436 mL of solution.
The activation energy for the isomerization ol cyclopropane to propene is 274 kJ/mol. By what factor does the rate of this reaction increase as the temperature rises
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