Determining the dose-response

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Based on the diagram below answer question 1:

1516_Sigmoid Dose-Response Curves for Three Carcinogems.jpg

1. Benzopyrene, 3-Methylcholanthrene and 1,2,5,6- Dibenzanthracene are three chemical carcinogens.

a. Rank the carcinogens in order of potency from more potent to less potent. Justify why you ordered them the way you did.

b. Rank the carcinogens in order of efficacy from higher efficacy to lower efficacy Justify why you ordered them the way you did.

For question 2, use the following dose response curve:

1403_analgesic efficacy of iv buprenorphine.jpg

1. This dose-response graph represents the analgesic efficacy of i.v. buprenorphine. 

a. In the same graph, draw a dose-response curve for a drug as efficient as buprenorphine but more potent. Why did you decide to place it there? (i.e., why did you move it left, right, up, down, etc.)

b. In the same graph, draw a dose-response curve for a drug less efficient but more potent. Why did you decide to place it there? (i.e., why did you move it left, right, up, down, etc.)

2. Based on the graph answer the following questions (For the purpose of this exercise, we are considering sugar doses as different drugs named Sugar0.3 and Sugar0.1.)

1198_Fermentation Dose Response.jpg

Reference no: EM133190966

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