Solution-Demonstrate the effect of oxygen transfer

Demonstrate the effect of oxygen transfer

Reference no: EM13874040 , Length:

In order to demonstrate the effect of oxygen transfer to tissue engineered constructs, Radisic et al proposed to carry out an experiment on a thick cylindrical porous scaffold with seeded cells.

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Due to the thickness of the scaffold, delivery of oxygen from the surrounding culture media to the center of the cylinder is very difficult. To do this they made a number of small cylindrical channels to which oxygen dissolved in culture media can flow and diffuse. A two-dimensional view is given below. Now consider the two small cylindrical channels shown below. The only way to deliver oxygen is by diffusion in the r direction from the flowing stream in the z direction. The oxygen concentration (Co) in the z direction is uniform. The oxygen consumption rate (V) in the r direction by the cells is zero order.

This is a tissue engineering problem about oxygen transfer

Reference no: EM13874040

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Demonstrate the effect of oxygen transfer : In order to demonstrate the effect of oxygen transfer to tissue engineered constructs, Radisic et al proposed to carry out an experiment on a thick cylindrical porous scaffold with seeded cells.

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Demonstrate the effect of oxygen transfer

Reference no: EM13874040 , Length:

Reference no: EM13874040

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