Compute the entropy of unfolding of lysozyme

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The protein lyzozyme unfolds at a transition temperature of 75.5 oC, and the standard enthalpy of transition is 509 kJ/mol. Calculate the entropy of unfolding of lysozyme at 25 oC, given that the difference in PCof unfolding is 6.28 kJ/mol/K at both 25 oC and 75 oC. Hint: consider a path of 25 oC (folded)?75.5 oC(folded) ?75.5 oC(unfolded) ?25 oC(unfolded).

Reference no: EM13191111

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