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The role of menstrual and reproductive factors in the epidemiology of breast cancer has been reassessed using pooled data from three large case-control studies of breast cancer from several Italian regions (Negri et al., 1988). In Table E1.24 data are summarized for age at menopause and age at first live birth.
Age at first live birth Cases Controls
22
621
898
22-24
795
909
25-27
791
769
b28
1043
775
Age at menopause
45
459
543
45-49
749
803
b50
1378
1167
(a) For each of the two factors (age at first live birth and age at meno- pause), choose the lowest level as the baseline and calculate the odds ratio associated with each other level.
(b) For each of the two factors (age at first live birth and age at meno- pause), calculate the generalized odds and give your interpretation. How does this result compare with those in part (a)?
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