Calculate the fraction of b alleles in the population

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The white "Spirit" black bear, Ursys anerucabys kermodei, differs from the ordinary black bear by a single amino acid change in the melanocortin 1 receptor gene. In this population, the gene has two forms (or alleles): the "white: allele b and the "black" allele B. The trait is recessive: white bears have two copies of the while allele of this gene (bb), whereas a bear is black if it has one ore two copies of the black allele (Bb or BB). Both colors morphs and all three genotypes are found together in the bear population of the northwest coast of British Columbia. If processing the white allele has no effect on growth, survival, reproductive success, or mating patterns of individual bears, then the frequency of individuals with 0, 1, or 2 copies of the white allele (b) in the population will follow a binomial distribution. To investigate, Hendrick and Ritland sampled and genotyped 87 bears from the northwest coast: 42 were BB, 24 were Bb, and 21 were bb. Assume that this is a random sampled of bears.

a. Calculate the fraction of b alleles in the population (remember, each bear has two copies of the gene).

proportion from the data

b. With your estimate of the fraction of b alleles, and assuming a binomial distribution, calculate the expected frequency of bears with 0, 1, and 2 copies.

Reference no: EM132389188

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