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1. 1000 molecules are bouncing at 300K between two wells separated by a free energy gap DG = 6·10-21 J. Calculate how many particles on average are in each well.Boltzmann constant k = 1.38 ·10-23 J/K T = 300K2. A clam-shell protein (see figure below) is more stable in its compact folded state by ?G = -50 kJ/mol than in its open state.a) What is the probability of being open for the intact protein? (give equilibrium constant Keq = [open]/[closed]) (T=300K) b) The pair of amino acids that forms a stabilizing hydrogen bond (14 kJ/mole) in the desolvated contact was replaced by alanines with almost no interaction. How many fold the probability of opening will increase in the mutant?
3. Calculate the Bjerrum length for pairs of ions (+2, +1) and (+2, +2) in water (e=80) at 300K.eo = 8.85 · 10-12 CV-1m-1 4. You know that one mole of water weights 18g and its density is 1g/cm3.a. Calculate density of bulk water (molecules/nm3) and surface density at the air-water interface (molecules/nm2) assuming that average intermolecular distances are the same. b. Given that tension at the air-water interface is 72 mN/m (enthalpy of surface formation) and enthalpy of average H-bond is 3.4 kcal/mole, how many H-bonds are dissatisfied at the surface? c. If average number of H-bonds in the bulk is 3.5/molecule, what fraction of bonds is dissatisfied at the surface?
Why use starved starved yeast rather than sugar fed yeasts for fermentation.What is the aim of ferementation after glycolysis.
It is commonly reported that up to 50 percent of a cell's energy budget is spent on protein synthesis. Think about the properties of two hypothetical genetic codes constructed with the four common nucleotides.
Check completed table correctly. A minus indicates that component or function is not present in the group and a plus indicates that it is.
In a population it was reported that the allele frequency for M was 80 percent and for N was 20 percent in the MN blood group. M and N are co-dominant.
Provided that a substance's permeability represents the distance it can travel in a lipid bilayer per unit time, how long would it take an uncharged.
Determine when a blood vessel bifurcates into two smaller vessels, the radii of the two smaller vessels add up to a larger cumulative radius than the radius of the original vessel.
Explain the procedures involved in blood doping. What are the physiological mechanisms behind blood doping that attempt to achieve the desired outcome.
The antibiotic anisomycin is expected to not inhibit the growth of bacteria and to inhibit the growth of Halobium. Anisomycin is resistant to bacteria,
Determine the genotypes of the parents, F1 offspring and F2 offspring and the probable mode of inheritance? Check your answer with the appropriate statistical test.
Explain the term convolution. Explain one of the image processing techniques in the spatial space for the medical imaging application.
Assume you identify five members of a multi-gene family that are expressed in the same tissues. All 5 genes appear to be equally expressed in all tissues.
Two genes located on separate autosomes determine flower color and shape. The gene for flower color exhibits incomplete dominance, where the color can be red.
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