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1-Suggest a destabilizing mutation and stabilizing mutation to helix 201-216. Briefly explain why your proposed mutations are predicted to be destabilizing and stabilizing, respectively. Provide pictures of your two mutant proteins2-Assume you have a protein x-ray structure. You are trying to validate the structure before using it in an in silico protein engineering experiment. You notice that the protein structure includes an Arg residues that is fully buried in the interior of the protein. Further analysis indicates that the Arg side chain fails to make any salt bridges or hydrogen bonds with other protein residues. This suggests that there is a problem with the protein structure. Every other validation calculation, however, indicates that the structure is a good one. Suggest a testable hypothesis that can account for the Arg data and support the inference that the protein structure is a good one.
To obtain a 18.0% (w/v) solution of copper sulfate (CuSO4), M.W = 160) when only the crystalline salt is available (CuSO4 x 5H2O, M.W. = 250) what should the crystalline salt be weight to prepare 450.0 mL of solution
If 28.0 mL of .150 M HCL is needed to neutralize all the NH3 from a 2.25-g sample of organic material, calculate the mass percentage of nitrogen in the sample.
Starting with 2.5 grams of vitamin D3 and 10mg of palladium catalyst, how many millimoles of H2 will be necessary to hydrogenate all of the Carbon Carbon double bonds in D3?
The specific heat capacity of the solution produced was 4.20J/g*Celcius, and final temp reached was 34.91 degrees c. How much heat was produced by the dissolution
The equilibrium constant KC for the reaction 2H2(g) + CO(g) ? CH3OH(g) is 135 at a certain temperature. If there are 5.23 ? 10?2 moles of H2 and 3.73 ? 10?
Choose the answer in which the two atoms are listed in order of increasing ionization energy
A sample of 0.255 mole of gas has a volume of 748 mL at 28°C. Calculate the pressure of this gas. (R= 0.0821 L · K)
Write a balance equations for both half-reactions for the redox. combine them to determine the overall balanced
A solution of .162 M NaOH is used to neutralize 25.0 mL of a H2SO4 solution. if 32.8mL of the NaOH solution is required to reach the endpoint, what is the molarity of the H2SO4 solution? H2SO4(aq)+2NaOH(aq)>Na2SO4(aq)+2H2O(l)
Problem- The reaction below takes place in a 250.0 mL flask at 23.8 C with SO2 having an initial pressure of 0.675 atm & O2 having an initial pressure of 0.335 atm
Write the electron configuration and shell diagram for each of the following elements: a) magnesium b) arsenic c) iodine
Explain Why a glacial Acetic acid in a conductance set-up does forms gradually brighter lights that is dim to bright because it is frequently diluted with water?
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