Radioisotopes, Biology


Radioisotopes are those forms of an element which exhibit rzdioactivity and so can be used as markers or tracers. For this purpose, we first introduce the radioisotope in a molecule in the cell and then detect the radioactivity with the help of certain device. For example, if we replace a suitable hydrogen atom of thymidine by 3H, we may trace the course of thymidine in the cell. Since thymidine is a component of DNA but not of RNA, we can be sure that we are following only DNA metabolism. Similarly, to know the course of protein synthesis we may use radioactively labelled amino acids.

Radioisotopes are used to:

(a) measure the rates of metabolic turnover of a material within a cell or tissue,

(b) locate the site of synthesis of molecules,

(c) measure the rate of exchange of materials across cellular membranes,

(d) locate a molecule in a cell. Radioisotopes are widely applied to study also the precursor-product relathship.

Many times when a radioactively labelled mokcule (pncursor) is introduced into a system. The molecule is chemically converted into another form (product). For example, when radioactive iron is introduced in blood, radioactivity can be detected in liver femtin and haemoglobin of red blood cells. Similarly, radioactivity of 32P- labelled phosphate can be detected in many phospholipids.

Posted Date: 12/10/2012 1:06:59 AM | Location : United States

Related Discussions:- Radioisotopes, Assignment Help, Ask Question on Radioisotopes, Get Answer, Expert's Help, Radioisotopes Discussions

Write discussion on Radioisotopes
Your posts are moderated
Related Questions
#question.what is the mechanism of circulatory system .

List the five kingdoms into which most living organisms can be classified. Most living organisms can be classified as a) Bacteria, b) Protozoa, c) Fungi, d) Plants,

What is epistasis? What is the difference between dominant epistasis and recessive epistasis? The Epistasis is the gene interaction in which a gene (the epistatic gene) able to

Why Nutrition is important for health Nutrition is one of the basic components of  life. It is an essential part of health care. You already know that good nutrition  is essent

General characteristics of phylum

Explain the Clinical manifestations for Obesity? You must have observed that your overweight friends and colleagues seem to have less energy which makes them an easy prey for f

How is the nervous system of nematodes organized? Where are the neural chords located in their body? Roundworms have a ganglial nervous system with an anterior neural ring sho

Materials Handling and Storage Material handling is a very significant process in working place. The materials are handled in not finished, semi finished and finished states.

Q. Give some Chlorine-releasing compound? Of all the chlorine - releasing compounds, hypochlorites have been the choice disinfectants used in food industry. The hypoc

Enumerate about the colour vision defects Acquired colour vision defects can occur afkr damage to the optic nerve or macula and in some cases, because of blue blindness in old