Radioisotopes, Biology

Radioisotopes

Radioisotopes are those forms of an element which exhibit rzdioactivity and so can be used as markers or tracers. For this purpose, we first introduce the radioisotope in a molecule in the cell and then detect the radioactivity with the help of certain device. For example, if we replace a suitable hydrogen atom of thymidine by 3H, we may trace the course of thymidine in the cell. Since thymidine is a component of DNA but not of RNA, we can be sure that we are following only DNA metabolism. Similarly, to know the course of protein synthesis we may use radioactively labelled amino acids.

Radioisotopes are used to:

(a) measure the rates of metabolic turnover of a material within a cell or tissue,

(b) locate the site of synthesis of molecules,

(c) measure the rate of exchange of materials across cellular membranes,

(d) locate a molecule in a cell. Radioisotopes are widely applied to study also the precursor-product relathship.

Many times when a radioactively labelled mokcule (pncursor) is introduced into a system. The molecule is chemically converted into another form (product). For example, when radioactive iron is introduced in blood, radioactivity can be detected in liver femtin and haemoglobin of red blood cells. Similarly, radioactivity of 32P- labelled phosphate can be detected in many phospholipids.

Posted Date: 12/10/2012 1:06:59 AM | Location : United States







Related Discussions:- Radioisotopes, Assignment Help, Ask Question on Radioisotopes, Get Answer, Expert's Help, Radioisotopes Discussions

Write discussion on Radioisotopes
Your posts are moderated
Related Questions
Describe the factors that affect cardiac output in a female athlete who is speed skating toward the finish line in an Olympic race

As the functions of individual genes become known, the power of this new biology can be used to change organisms in predictable and desirable pathways.  Organisms which have been c

What are the major plant tissues that form the rings observed on stem sections of some trees? The rings observed on a stem cross section of the dicot trees are made of conducti

what so special for phylum annelida

Q. Of which type of defense cell do worm infections stimulate the multiplication? The main leukocytes that generally participate and multiply in the defense against worm infect

what is the composition of urine in fishes and reptiles ?

What are some of the presumed target substrates for cyclin-dependent kinases?


What is right patellar tendon Which of the following occur in response to an increase in the length of the right knee extensors in response to a quick tap applied to the right

What is the lymphatic system? The lymphatic system is a network of specialized valved vessels that drain interstitial fluid (lymph). The lymphatic system is also responsible fo