Procedures for diagnosis - monoclonal antibodies, Biology

Monoclonal antibodies:

Hybridoma technology for production of monoclonal antibodies is one of the most important advancements in the field of immunology. Monoclonal antibodies (Mabs) have been extensively used for the diagnosis of wide spectrum of viral and other infectious diseases, analysis of important immunogenic regions (epitopes) for better control and prevention of diseases. The Mabs can be used with advantage of high sensitivity and specificity in enzyme linked immunosorbent assay (ELISA), neutralization and other serological tests. Use of Mabs in ELISA provides useful aid to the epidemiologist in the differentiation of virus strains and tracing the source of outbreak with greater certainty. The Mabs are also used, profitably to differentiate the rinderpest from peste des petits ruminant (PPR) virus, different strains of bovine viral diarrhoea, foot-and- mouth disease virus strains, study of antigenic variation in equine influenza, understanding the immunobiology and development of antigenic variants of equine infectious anaemia (EIA) virus in persistent infection; differentiation between EHV-I and EHV-IV and between North and South American strains of eastern equine encephalomyelitis and other closely related virus strains/isolates. With the advent of fluorescence-activated cell sorter (FACS), cell surface markers can be tagged with monoclonal antibodies for their identification and quick screening of population of particular cell type or biomarker on the cell surface.

Posted Date: 9/19/2012 1:20:32 AM | Location : United States







Related Discussions:- Procedures for diagnosis - monoclonal antibodies, Assignment Help, Ask Question on Procedures for diagnosis - monoclonal antibodies, Get Answer, Expert's Help, Procedures for diagnosis - monoclonal antibodies Discussions

Write discussion on Procedures for diagnosis - monoclonal antibodies
Your posts are moderated
Related Questions
Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4

Explain the Alternaria - Fungi? Classification Kingdom - Mycetae Division - Amastigomycota Form Class - Deuteromycetes Form Subclass - Hyphomycetidae Form Order

What are the Temporal Factors of Abnormality Given the on going schedule of postnatal neurodevelopment, the age of the child at the time of exposure and the behaviour can have

What is cloning? Cloning is the making of an organism genetically the same to another by means of genetic engineering. The basis of cloning is the nucleus transplantation ma

What is linkage? Two genes are assumed to be under linkage, or linked, when they reside in the same chromosome. For instance, the research of the human genome discovered tha


Explain the blood vitreous barrier as the physio-chemical property. Blood Vitreous Barrier: The blood vitreous barrier consists of three components: Tight junctional comp

Q. What is the antagonism between the sympathetic and the parasympathetic neural actions? In general the action of the parasympathetic and the sympathetic are antagonistic that

Staphylococcal food poisoning results from consumption of food containing enterotoxin produced by enterotoxigenic strains of Staphylococcus aureus. It is caused by ingestion of imp

S T ARC H - Polymer of a-D-glucose. Starch is glucosan homopolysaccharide which is the major reserve food of plants. Starch is formed as an end product of photosynt