Poultry and duck diseases-avian leucosis complex (alc), Biology

Avian leucosis complex (ALC)

The disease in poultry is caused by an RNA virus classified under avian type C Retrovirus group under the family Retroviridae.

Epidemiology: Avian leucosis viruses are endemic in virtually all flocks of chickens. The clinical manifestation is sporadic in birds over 14 weeks of age with an incidence rate of around 3%. However, in some lines of birds the incidence rate may reach up to 20%.

Symptoms: The clinical sings in affected birds show pale comb, shriveled, cyanotic and enlarged abdomen. On autopsy, tumors occur in liver, spleen, bursa and in a few other internal organs. Microscopically the lesions reveal multicentric aggregates of lymphoblasts.

ALC is diagnosed by complement fixation test (CFT), radioimmunoassay (RIA) and ELISA for group specific antigens. Tests for reverse transcriptase, immunohistochemical tests; virus isolation methods etc. are available for laboratory confirmation of the disease. There is no effective vaccine available to control this disease.
Treatment and control: It is controlled through

(i) establishing leucosis - free breeding flocks by a routine screening and breeding programme

(ii) strict hygienic conditions on the premises to ward off lateral transmission of the virus

(iii) encouraging breeds derived from ALC- resistant flocks.

Posted Date: 9/18/2012 9:26:47 AM | Location : United States

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