Nicotinic acid or niacin, Biology

Assignment Help:

Niacin affects all lipid parameters favorably. It is one of the only agents that reduces Lp (a) significantly (up to 30 per cent). Unfortunately, compliance is poor because of frequent side effects. Flushing and pruritus, gastrointestinal discomfort, glucose intolerance, and hyperuricemia often accompany use of niacin, hepatotoxicity is rare but is more commonly seen with the sustained released preparation. It is often heralded by a dramatic reduction in lipid levels. There are limited data on long-term therapy with this agent. Niacin may be particularly useful for patients who do not have substantial elevations in their LDL-C levels, and low doses may be used to treat diabetic dyslipidemia. High doses should be avoided in those with a history of gout, peptic ulcer disease, or active hepatic disease. Extended release preparations are to be used and not sustained release ones.


Related Discussions:- Nicotinic acid or niacin

Systolic dysfunction onset of symptoms, Q. Systolic dysfunction onset of sy...

Q. Systolic dysfunction onset of symptoms? In asymptomatic patients with normal LV function, the rate of progression to symptoms and/or LV Systolic dysfunction is about 4 per c

Classification, what is binomial nomenclature? What are the importance of i...

what is binomial nomenclature? What are the importance of it?

Anti-malarial drugs kill the parasites in the blood, (a) Anti-malarial drug...

(a) Anti-malarial drugs kill the parasites in the blood but they do not cure the disease.Why is this? (b) Why was the use of DDT insecticide not successful in eradicating mal

Analyze the chromosomes of her daughters or of her sons, Is it more indicat...

Is it more indicated for a geneticist desiring to map the X chromosome of the mother of a given family (the researcher does not have access to her DNA, only access to the genetic m

#title a&p, list all of the parts of a generalized cell that might be invol...

list all of the parts of a generalized cell that might be involved support movement coordination respiration digestion transportation excr production making proteins and reproducti

Esophageal obstruction, E s o pha g e a l obstruction It is also...

E s o pha g e a l obstruction It is also known as choke. It may be acute or chronic and is characterized by inability to swallow, regurgitation and bloat. E t

Explain the both sex-linked trait and a sex-influenced trait, Explain the d...

Explain the difference among a sex-linked trait and a sex-influenced trait. A sex-influenced trait is influenced by the presence of sex hormones and its genes are not situated

Explain poor growth - clinical signs of kwashiorkor, Explain Poor growth - ...

Explain Poor growth - clinical signs of kwashiorkor? Growth retardation is the earliest manifestation of kwashiorkor, the child will be lighter and shorter than its normal peer

The principal nitrogenous excretory in humans, The principal nitrogenous ex...

The principal nitrogenous excretory compound in humans is synthesised: 1. in kidneys but eliminated mostly through liver 2. in kidneys as well as eliminated by kidneys 3.

What is the second polar body, Q. What is the second polar body? After ...

Q. What is the second polar body? After termination of the second meiotic division of the oocyte II two cells are generated: the second polar body and the egg cell proper. The

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd