Explain adverse effects of cidofovir, Biology

Assignment Help:

Explain Adverse Effects of Cidofovir

About 25% of patients discontinue cidofovir because of adverse effects such as nephrotoxicity, neutropenia and metabolic acidosis. Iritis, uveitis or ocular hypotony can happen. To decrease the risk of nephrotoxicity, IV 0.9% saline and oral probenecid must be given with each cidofovir dose. Cidofovir is contraindicated in patients taking other nephrotoxic agents. Adverse effects are more common in patients at the same time taking antiretroviral drugs. The drug is oncogenic in animals. Topical cidofovir (not commercially available) causes local irritation and ulceration, especially in concentrations of 3% or higher.

 


Related Discussions:- Explain adverse effects of cidofovir

Excretory organs, classification of excretory organs in helminthes, nermato...

classification of excretory organs in helminthes, nermatodes, annelids, molluscs, arthropods and echinodems

Acute mitral regurgitation-mitral regurgitation, Acute Mitral Regurgitation...

Acute Mitral Regurgitation :  This may be caused by chordal rupture, infective endocarditis or acute myocardial infarction. In acute myocardial infarction, one of the papilla

State three main ways in which the body uses food, State three main ways in...

State three main ways in which the body uses food. The body uses food (i) for energy, (ii) for growth (making new cells), (iii) repairing or replacing tissues.

Humans have selectively bred many radically, Humans have selectively bred m...

Humans have selectively bred many radically different domestic animals(e.g., St. Bernard and Chihuahua dog breeds). Does this activity result in evolution? why or why not?

Define essential parts of photocolorimeter - light source, Define Essential...

Define Essential Parts of Photocolorimeter - Light Source? The light source is usually a tungsten lamp, for wavelength in the visible range (320-700 nm) and a deuterium or hydr

Chitin, CHITIN It is polymer of N-acetyl-D-glucosamine. It is a s...

CHITIN It is polymer of N-acetyl-D-glucosamine. It is a structural homopolysaccharide found in the fungal walls as fungus cellulose and as chitin in the exoskeleton of

Explain measles, Measles Adults born after 1956 who have not received ...

Measles Adults born after 1956 who have not received 2 doses of live measles vaccine (not the killed vaccine that was commonly used in the 1960s) after their first birthday an

Endocrine system, Endocrine System The nervous system brings about in...

Endocrine System The nervous system brings about integration and co-ordination of several activities of the animal. The afferent stimuli from several sense organs are brought

Cell wall, Cell wall is the structure produced by some of the cells outsid...

Cell wall is the structure produced by some of the cells outside their cell membrane; variously composed of the chitin, peptidoglycan, or cellulose.

Write Your Message!

Captcha
Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd