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Disorders of pancreas, Biology
S OF THE PANCREAS -
) Diabetes mellitus (Hypoinsulinism)
The insulin-dependent diabetes mellitus (IDDM) is caused by a failure of the Beta-cells to produce adequate amounts of insulin while the non-insulin-dependent diabetes mellitus (NIDDM) appears to involve failure of insulin to facilitate the movement of glucose into cells.
Glucose is excreted by urine, if amount of glucose is in excess in the blood, this is known as "
". In this stage, amount of glucose in blood increases upto > 180 mg./dl. of blood. It is diabetes mallitus disease.
Polyurea, polydipsia (the patient feel thirsty), keto acidosis (ketone bodies formed in the body).
The combined effect of ketoacidosis, dehydration and hyperglycemia may cause diabetic comma to the patient, patient becomes unconscious and even may die.
Insulin harmone is given to the patient by injection in this disease, insulin given orally is not effective, because it is digested in the alimentary canal like protein.
Now a days oral insulin is used in following states - (a) IZS - Insulin zinc suspension (b) PZI - Protamine zinc insulin
Glucose decreases in blood.
Insulin shock - At the time of physical labour or fasting, if a diabetic patient takes an insulin injection, sugar level in blood reduces quickly up to 43 mg/100 ml of blood. It is called insulin shock. The patient may be unconscious or even may die.
Posted Date: 10/2/2012 7:07:44 AM | Location : United States
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