Disorder of adrenal function, Biology

Disorder  of Adrenal Function:

The disorders of  adrenal function may lead  to acute and chronic  .adrenocortical insufficiency. Let  us briefly  describe each  one as follows. 

Acute Adrenocortical Insufficiency:

This  is a rare  disorder and may  result from  variety  of  causes  such  as haemorrhage  in glands from trauma due  to  difficult labour, meningococcal infections and or  abrupt withdrawal  of  exogenous sources  of  cortisone or failure to increase exogenous supplies  during stress or congenital  adreno genital hyperplasia. Management includes replacement of  cortisol,  body fluids  to correct dehydration  and hypovolemia administration of glucose  to correct hypoglycemia and specific antibiotic  therapy. Blood transfusion  is given  if  haemorrhage  is severe. 

Chronic Adrenocortical  Insufficiency (Addison's Disease):

This disorder rarely occurs in children. It  is caused  by  destructive lesion  of  the adrenal glands or a neoplasm, or  it  is  idiopathic. The child may present with neurologic symptoms such as muscular weakness, mental fatigue, irritability pigmentry changes,  palinar creases, hyperpigmentation over pressure points, dehydration, anorexia weight loss, headache, hunger, sweating  and weakness etc. Therapeutic  treatment includes replacement of cotisol and aldosterone. 

Cushing Syndrome:

Cushings syndrome  is uncommon  in children.  It  is a characteristic group  of manifestations caused  by  excessive circulating  free cortisol. (Fig.  5.2).  It may occur  due  to one or more of the following causes: 

Pituitary with adrenal hyperplasia, usually attributed  to an  excess of ACTH  

Adrenal with hypersecretion of  glucocorticoids, generally the result of adrenocortical neoplasms 

Ectopic with autonomous secretion  of ACTH, most often caused  by extrapituitary neoplasms Iatrogenic,  frequently the result of administration of  large amounts of exogenous coricosterioids Food  dependent,  inappropriate sensitivity  of  adrenal glands to normal postprandial increases in  secretion of  gastric inhibitory polypeptide Therapeutic management involves bilateral adrenalectomy and post operative replacement of the cortical hormgnes.  

Posted Date: 10/26/2012 8:38:32 AM | Location : United States







Related Discussions:- Disorder of adrenal function, Assignment Help, Ask Question on Disorder of adrenal function, Get Answer, Expert's Help, Disorder of adrenal function Discussions

Write discussion on Disorder of adrenal function
Your posts are moderated
Related Questions
SERENDIPIDIT Y - Sometimes discoveries are made unexpectedly matter of chance. This is serendipidity. Examples - 1.       Structural formula of benzene - It was dreamt by

Define Polyacrylamide gel electrophoresis (PAGE)? Acrylamide gel has the advantage over starch in that it is easier to prepare and is more inert, the pore size can be varied in

how do we write a limerick spell?

Define the Spatial processes? Environmental and integrative biology cuts across a wide array of spatial scales, and theoretical approaches that take into account these widely v

Q. Moniliasis is one of the most common opportunistic diseases in AIDS. What is the etiological agent of moniliasis and what is the other name of the disease? Why is monilia also c

Define Effect of Enery on quality and quantity of human milk? Energy: In case of chronic under nutrition, an association between postpartum weight loss and lower energy transfe

Give definitions of atomic number and atomic mass and how they relate to protons, neutrons, and electrons in neutral atoms?

What are some of the presumed target substrates for cyclin-dependent kinases?

Why are producers the first trophic level to advantage from the activity of decomposers? Decomposers return nutrients in dead tissues and wastes to the soil or water; producers

Left Antero Lateral Thoracotomy Approach :  Arterial and central venous pressure monitoring lines are placed. A left antero lateral thoracotomy is done through the 5th or 4th