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Which of the following statements regarding the interactions among sequence-specific DNA binding domains and their recognition sites is incorrect?
A. Sequence-specific DNA binding domains use alpha helical structures to interact with nucleotides within the main groove.
B. Multiple sequence-specific developmentally regulated DNA binding proteins can concurrently bind to an enhancer element.
C. The quality of the binding site will influence both the residency time of a DNA binding protein at the enhancer and the level of transcriptional output from the enhancer.
D. Sequence-specific DNA binding proteins recruit RNA Pol II to the enhancer element.
Nuclease is an enzyme which degrades the nucleic acids. A nuclease can be DNA-specific (a DNase), RNA-specific (RNase) or non-specific. It might act only on single stranded nuclei
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Can someone explain how is cancer related to ras and p53 gene? I know that the ras protein regulate cell growth and its mutation will cause cancer. How is the mutation caused?
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