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Q. Conditions Necessary for outbreak of botulism?
The following conditions are necessary for an outbreak of botulism:
1. Presence of spores of C. botulinum of type A, B or E in foods being consumed or being processed in some other way
2. A food in which the spores can germinate and the clostridia can grow and produce toxin
3. Survival of the spores of C. botulinum because of inadequate heating in canning or inadequate processing otherwise
4. Environmental condition after processing that will permit germination of the spores and growth and toxin production by the organism
5. Insufficient cooking of the food to inactivate the toxin
6. Ingestion of the toxin-bearing food
MOD E OF HORMONE ACTION THROUGH INTRACELLULAR RECEPTORS - Steroid hormones are lipid-soluble and easily pass through the cell membrane of a target cell into the cytoplasm.
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