Classification of nephrotic syndrome, Biology

Classification of Nephrotic Syndrome

In childhood, nephrotic syndrome can be divided into minimal lesion nephrofic syndrome and  significant lesion nephrotic syndrome depending upon renal histological characteristics and response to corticosteroids and selective proteinuria. About 80  to 85 per cent of  children with nephrotic syndrome are of minimal lesion. 

Minimal lesion nephrotic syndrome currently called as minimal change nephrotic syndrome (MCNS) is corticosteroid responsive. The kidney in MCNS appears normal under light microscope and under electron microscope it shows fusion of epithelial cells ''Foot  processes" which is the minimal change. In minimal lesion only albumin is filtered. In significant lesion glomerulo nephritis, glomerulus shows an area of scarring which is attributed to the passage of  large amounts of  protein across the glomerular basement membrane. The sclerosis may be seen only  in very few deep glomeruli. In  this type of glomerulo nephritis 80 per cent will not respond to steroid therapy. 

As you have seen there are two types of  glomerular nephritis as given below: 

a)  Minimum Lesion Nephrotic Syndrome (MLNS) 

b)  Significant Lesion Nephrotic Syndrome (SLNS)  

Posted Date: 10/27/2012 1:16:43 AM | Location : United States







Related Discussions:- Classification of nephrotic syndrome, Assignment Help, Ask Question on Classification of nephrotic syndrome, Get Answer, Expert's Help, Classification of nephrotic syndrome Discussions

Write discussion on Classification of nephrotic syndrome
Your posts are moderated
Related Questions
Braxy The causative agent of braxy is Cl. septicum. It usually affects lambs. The agent is a normal inhabitant of soil and is frequently found in the faeces of herbivores. Bra

Q. Embryology in relation to taxonomy? Embryological information has been used for taxonomic purposes at various levels of classification. You know of a very basic division of


Types of Organization Chart: There are  two important  types of organization chart.  a)  Vertical i.e.,  from top to bottom.  b)  Horizontal  i.e., from  left to right.

Define the role of riboflavin in Drug and lipid metabolism? Flavoproteins catalyze dehydrogenation reactions, as well as, hydroxylations, oxidative decarobxylations, deoxygenat

Which of the following is an active transport process? A. Net flux of sodium across the plasma membrane via voltage-gated sodium channels. B. Net flux of glucose across the

list the major species of echinodermata

Which of the below is usually referred to as "master gland" because it regulates so many body activities? Is it: a) Pituitary gland b) Thyroid gland c) Adrenal gland d

Pyramid of Energy - Ecological Pyramids When we wish to compare the functional roles of the trophic levels in an ecosystem, an energy pyramid is probably the most informative.

Determine the categories of sleep disorders Sleep disorders are generally divided into two major groups: 1) Narcolepsy, which is characterised by excessive sleep or brief in